{"id":28318,"date":"2019-11-16T13:13:19","date_gmt":"2019-11-16T10:13:19","guid":{"rendered":"http:\/\/ihcoedu.uobaghdad.edu.iq\/?p=28318"},"modified":"2020-01-19T14:06:38","modified_gmt":"2020-01-19T11:06:38","slug":"%d9%82%d8%b3%d9%85-%d8%a7%d9%84%d9%83%d9%8a%d9%85%d9%8a%d8%a7%d8%a1-%d9%8a%d9%86%d8%a7%d9%82%d8%b4-%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1-%d8%aa%d8%ad%d8%b6%d8%b1","status":"publish","type":"post","link":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=28318","title":{"rendered":"\u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u064a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u062a\u062d\u0636\u0631 \u0628\u0639\u0636 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u062d\u0644\u0642\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u062c\u0627\u0646\u0633\u0629 \u0648\u062a\u062f\u0631\u0633 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0647\u0627"},"content":{"rendered":"

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 <\/p>\n

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\u0627.\u062f \u0639\u0644\u064a \u062d\u0645\u0627\u062f\u064a \u0633\u0645\u064a\u0631\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u0631\u0626\u064a\u0633\u0627<\/span><\/h4>\n

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\u0627.\u0645.\u062f. \u0627\u0633\u0645\u0627\u0639\u064a\u0644 \u064a\u0627\u0633\u064a\u0646 \u0645\u062c\u064a\u062f\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u0639\u0636\u0648\u0627 \u0648\u0645\u0634\u0631\u0641\u0627<\/span><\/h4>\n

\"\"\"\"\u0648\u062a\u0647\u062f\u0641 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0649 \u062a\u062d\u0636\u064a\u0631 \u0645\u0631\u0643\u0628\u0627\u062a\u00a0\u00a0 DIQUAINAZOLINE\u062c\u062f\u064a\u062f\u0629 \u0645\u0628\u062a\u062f\u0626\u0627\u064b \u0645\u0646 \u062d\u0627\u0645\u0636 \u0627\u0644\u0627\u0648\u0643\u0632\u0627\u0644\u064a\u0643 \u0648\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0644\u0647\u0627.<\/span><\/h4>\n

<\/h4>\n

\u0648\u062a\u0636\u0645\u0646 \u0627\u0644\u0639\u0645\u0644 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u062d\u0644\u0642\u064a\u0629 \u0627\u0644\u063a\u064a\u0631 \u0645\u062a\u062c\u0627\u0646\u0633\u0629 \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u062d\u0644\u0642\u0629 (\u0627\u0644\u0645\u062a\u0646\u0627\u0638\u0631\u0629) \u0648\u0647\u064a \u0645\u0634\u062a\u0642\u0627\u062a \u062d\u0644\u0642\u0629 \u0627\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646.<\/span><\/h4>\n

\u062d\u064a\u062b \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628[\u00a0 A]\u00a0 4H,4’H-[2,2′-bibenzo[d][1,3]oxazine]-4,4′-dione\u00a0 \u0648\u0630\u0644\u0643 \u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0643\u0644\u0648\u0631\u064a\u062f \u0627\u0644\u062d\u0627\u0645\u0636 (oxalyl chloride) \u0645\u0639 (2\u0645\u0648\u0644) \u0645\u0646 ) 2-aminobenzoic acid) \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0628\u0631\u064a\u062f\u064a\u0646 \u0648\u0627\u0644\u0645\u0627\u0621\u060c \u062d\u064a\u062b \u0627\u0646 \u0627\u0644\u0645\u0631\u0643\u0628 [A] \u0647\u0648 \u0627\u0644\u0627\u0633\u0627\u0633 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644 \u0644\u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u062c\u062f\u064a\u062f\u0629.<\/span><\/h4>\n

\u062d\u064a\u062b:-<\/span><\/h4>\n

1-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062a\u0645 \u0645\u0641\u0627\u0639\u0644\u0629 \u0627\u0644\u0645\u0631\u0643\u0628 [A] \u0645\u0639 \u0627\u0644\u0647\u064a\u062f\u0631\u0627\u0632\u064a\u0646 \u0627\u0644\u0645\u0627\u0626\u064a 80% \u0644\u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642 \u0627\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u0630\u064a \u064a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0645\u064a\u0646 \u0627\u0648\u0644\u064a\u0629 \u0645\u0631\u0643\u0628 [B]\u060c \u0648\u0627\u0644\u0630\u064a \u062a\u0645 \u0645\u0641\u0627\u0639\u0644\u062a\u0647 \u0645\u0639:-\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u0623- \u0633\u0644\u0633\u0629 \u0645\u0646 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0644\u0628\u0646\u0632\u0627\u0644\u062f\u064a\u0647\u0627\u064a\u062f \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a [P,G,H,I,E,D,X].\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u0628-\u00a0 \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642 \u0644\u0644\u0627\u0645\u064a\u062f\u0627\u062a \u0627\u0644\u062d\u0644\u0642\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0645\u0631\u0643\u0628\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 [B]\u00a0 3,3,-diamino-[2,2′-biquinazoline]-4,4′(3H,3’H)-dione \u0645\u0639 (2\u0645\u0648\u0644) \u0645\u0646 \u0627\u0644\u0627\u0646\u0647\u062f\u0631\u064a\u062f\u0627\u062a \u0627\u0644\u062d\u0644\u0642\u064a\u0629 )\u0627\u0646\u0647\u062f\u0631\u064a\u062f \u0627\u0644\u0641\u062b\u0627\u0644\u0643\u060c \u0627\u0646\u0647\u062f\u0631\u064a\u062f \u0627\u0644\u0645\u0627\u0644\u064a\u0643( \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628 [Ph,Ma].<\/span><\/h4>\n

2-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0633\u0644\u0641\u0648\u0646 \u0627\u0645\u0627\u064a\u062f \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0644\u0645\u0627 \u0644\u0647\u0627 \u0645\u0646 \u0627\u0647\u0645\u064a\u0629 \u0643\u0628\u064a\u0631\u0629 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u062d\u064a\u062b \u062a\u0641\u0627\u0639\u0644 \u0645\u0631\u0643\u0628 \u0627\u0644\u0633\u0644\u0641\u0627\u062b\u0627\u064a\u0627\u0632\u0648\u0644 \u0645\u0639 \u0627\u0644\u0645\u0631\u0643\u0628 [A] \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628 [M]\u00a0 4,4′-(4,4′-dioxo-2,2′-biquinazoline -3,3′(4H,4’H)-diyl ) bis (N-(thiazol-2-yl ) benzenesulfonamide<\/span><\/h4>\n

\u0648\u0645\u0646 \u062b\u0645 \u0628\u062a\u0641\u0627\u0639\u0644 \u0627\u062e\u0631 \u062a\u0645 \u0645\u0641\u0627\u0639\u0644\u0629 \u0627\u0644\u0633\u0644\u0641\u0627\u062f\u0627\u064a\u0627\u0632\u064a\u0646 \u0645\u0639 \u0627\u0644\u0645\u0631\u0643\u0628 [A] \u0644\u063a\u0631\u0636 \u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628 [N]<\/span><\/h4>\n

4,4′-(4,4′-dioxo-2,2′-biquinazoline-3,3′(4H,4’H)-diyl)bis(N-(pyrimidin-2-yl) benzenesulfonamide<\/span><\/h4>\n

\u062d\u064a\u062b \u0627\u0639\u0637\u062a \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0641\u0639\u0627\u0644\u064a\u0629 \u062c\u064a\u062f\u0629 \u0636\u062f \u0628\u0639\u0636 \u0627\u0646\u0648\u0627\u0639 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u0644\u062a\u064a \u062a\u0645 \u0642\u064a\u0627\u0633\u0647\u0627 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644.<\/span><\/h4>\n

<\/h4>\n

3-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u062c\u062f\u064a\u062f\u0629 \u0644\u0645\u0631\u0643\u0628 \u062b\u0646\u0627\u0626\u064a \u0627\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646 \u0627\u0644\u0645\u0631\u0643\u0628\u064a\u0646 (W \u0648Z )\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n

N,N’-((4,4′-dioxo-[2,2′ biquinazoline] -3,3′(4H,4’H)-diyl) bis (4,1-phenylene)) diacetamide [W]\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n

3,3′-bis(4-acetylphenyl)-[2,2′-biquinazoline] -4,4′(3H,3’H)-dione [Z]\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n

\u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0641\u0627\u0639\u0644 \u0645\u0634\u062a\u0642 \u0627\u0644\u0627\u0646\u0644\u064a\u0646 ( (4-amino acetophenone ,4-amino acetanilide \u0645\u0639 \u0627\u0644\u0645\u0631\u0643\u0628 [A].<\/span><\/h4>\n

4-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u062c\u062f\u064a\u062f\u0629 \u0627\u062e\u0631\u0649 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u062d\u0644\u0642\u062a\u064a\u0646 \u0645\u0646 \u0627\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646 \u062d\u064a\u062b \u062a\u0645 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u062c\u0632\u0621 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0645\u064a\u0646\u0627\u062a \u0627\u0648\u0644\u064a\u0629 \u062a\u062d\u062a\u0648\u064a \u0641\u064a \u062a\u0631\u0643\u064a\u0628\u0647\u0627 \u0639\u0644\u0649 \u0645\u0631\u0643\u0628\u0627\u062a \u062d\u0644\u0642\u064a\u0629 \u063a\u064a\u0631 \u0645\u062a\u062c\u0627\u0646\u0633\u0629 \u0645\u062b\u0644 \u0627\u0644\u0641\u064a\u0648\u0631\u0627\u0646 \u062d\u064a\u062b \u0627\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0641\u064a\u0648\u0631\u0627\u0646 \u0627\u0644\u0645\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0647\u064a\u062f\u0631\u0627\u0632\u0627\u064a\u062f \u0648\u0643\u0630\u0644\u0643 \u0627\u0633\u062a\u062e\u062f\u0645 \u0645\u0631\u0643\u0628\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 2-aminobenzothiazole)) \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0627\u0644\u0649 \u0645\u0631\u0643\u0628\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 ((3-amino-2-phenylquinazolin-4(3H)-one \u0648\u0643\u0630\u0644\u0643 \u0645\u0631\u0643\u0628 \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u0645\u064a\u0643\u0627\u0631\u0628\u0627\u0632\u0627\u064a\u062f \u0648\u0630\u0644\u0643 \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a<\/span><\/h4>\n

N,N’-(4,4′-dioxo-[2,2′-biquinazoline]-3,3′(4H,4’H)-diyl)bis(furan-2-carboxamide) (Q)<\/span><\/h4>\n

3,3′-bis(benzo[d]thiazol-2-yl)-[2,2′-biquinazoline]-4,4′(3H,3’H)-dione\u00a0 [T]<\/span><\/h4>\n

2,2”’-diphenyl-4H,4’H,4”H,4”’H-[3,3′:2′,2”:3”,3”’-quaterquinazoline]- 4,4′,4”,4”’-tetraone\u00a0 [R]\u00a0<\/span><\/h4>\n

1,1′-(4,4′-dioxo-[2,2′-biquinazoline]-3,3′(4H,4’H)-diyl)bis(thiourea) [L]\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n

5-\u00a0\u00a0\u00a0\u00a0\u00a0 \u0627\u0645\u0627 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0627\u062e\u064a\u0631 \u0641\u0642\u062f \u062a\u0636\u0645\u0646 \u062a\u062d\u0636\u064a\u0631 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u062c\u0627\u0644\u0643\u0648\u0646\u0627\u062a \u0648\u0627\u0644\u0645\u062d\u0636\u0631\u0629 \u0633\u0627\u0628\u0642\u0627\u064b \u0627\u0644\u062a\u064a \u062a\u062d\u062a\u0648\u064a \u0641\u064a \u062a\u0631\u0643\u064a\u0628\u0647\u0627 \u0639\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u062d\u0631\u0629 \u0645\u0646 \u0627\u0644\u0627\u0648\u0644\u064a (NH2-) \u062d\u064a\u062b \u062a\u0645 \u062a\u062d\u0636\u064a\u0631\u0647\u0627 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 (4-aminoacetophenone) \u0645\u0639 \u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0644\u0628\u0646\u0632\u0627\u0644\u062f\u064a\u0647\u0627\u064a\u062f \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u062c\u0627\u0644\u0643\u0648\u0646\u0627\u062a [K2,K3,K5,K6] \u0628\u0639\u062f\u0647\u0627 \u062a\u0645 \u0645\u0641\u0627\u0639\u0644\u0629 \u0647\u0630\u0647 \u0627\u0644\u062c\u0627\u0644\u0643\u0648\u0646\u0627\u062a \u0645\u0639 \u0627\u0644\u0645\u0631\u0643\u0628\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 4H,4’H-[2,2′-bibenzo[d][1,3]oxazine]-4,4′-dione \u0644\u062a\u062d\u0636\u064a\u0631 \u0633\u0644\u0633\u0644\u0629 \u0645\u0646 \u0645\u0631\u0643\u0628\u0627\u062a \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646 \u0648\u0627\u0644\u062a\u064a \u062a\u062d\u062a\u0648\u064a \u0641\u064a \u062a\u0631\u0643\u064a\u0628\u0647\u0627 \u0639\u0644\u0649 \u0648\u062d\u062f\u0629 (\u03b1, \u03b2- unsaturated group) \u0648\u0647\u064a \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a [AK2,AK3,AK5,AK6].<\/span><\/h4>\n

6-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062a\u0645 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u062d\u064a\u062b \u0627\u0638\u0647\u0631\u062a \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0641\u0639\u0627\u0644\u064a\u0629 \u062c\u064a\u062f\u0629 \u0636\u062f \u0628\u0639\u0636 \u0627\u0646\u0648\u0627\u0639 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0648\u0647\u064a Staphylococcus\u00a0 aureus , Bacillus subtilis\u00a0 , ( Escherichia Coli\u00a0\u00a0 (and Pseudomonas aeruginosa<\/span><\/h4>\n

\u062a\u0645 \u062a\u0648\u0636\u064a\u062d \u0630\u0644\u0643 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062c\u062f\u0648\u0644 (3-6) \u0648\u0627\u0644\u0630\u064a \u064a\u0648\u0636\u062d \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0644\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644.<\/span><\/h4>\n

<\/h4>\n

\u0648\u0627\u0648\u0635\u0649 \u0627\u0644\u0637\u0627\u0644\u0628 \u0641\u064a \u0646\u0647\u0627\u064a\u0629 \u0631\u0633\u0627\u0644\u062a\u0647 \u0628\u0627\u0644\u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u062a\u0627\u0644\u064a\u0629 :<\/span><\/h4>\n

1-\u00a0\u00a0\u00a0\u00a0\u00a0 \u064a\u0645\u0643\u0646 \u062a\u062d\u0636\u064a\u0631 \u0645\u0634\u062a\u0642\u0627\u062a \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u0643\u0648\u064a\u0646\u0627\u0632\u0648\u0644\u064a\u0646 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0645\u0631\u0643\u0628 [A] \u0645\u0639 \u0627\u0645\u064a\u0646\u0627\u062a \u0627\u0648\u0644\u064a\u0629\u062c\u062f\u064a\u062f\u0629.<\/span><\/h4>\n

2-\u00a0\u00a0\u00a0\u00a0\u00a0 \u064a\u0645\u0643\u0646 \u062a\u062d\u0636\u064a\u0631 \u0642\u0648\u0627\u0639\u062f \u0634\u0641 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0645\u0631\u0643\u0628 [B] \u0645\u0639 \u0627\u0644\u062f\u064a\u0647\u0627\u064a\u062f\u0627\u062a \u0627\u0648\u0631\u0645\u0627\u062a\u064a\u0629 \u062c\u062f\u064a\u062f\u0629.<\/span><\/h4>\n

3-\u00a0\u00a0\u00a0\u00a0\u00a0 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0641\u0637\u0631\u064a\u0627\u062a \u0644\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629.<\/span><\/h4>\n

 <\/p>\n

\n

Synthesis\u00a0 and\u00a0 Evaluating of antibacterial Activity of Some New Heterocyclic Compounds<\/span><\/h3>\n

By\u00a0 Ameer Ali Hussein<\/span><\/h3>\n

Supervised by Assist. Prof. Dr. Ismail .Y. Majeed<\/span><\/h3>\n

Abstract<\/span><\/h3>\n

This thesis contains synthesis of some new derivative of di heterocyclic compounds (di quinazoline compounds<\/span><\/h3>\n

Compound (A) was prepared by the reaction of oxalyl chloride with (2mols) of anthranilic acid in pyridine and water<\/span><\/h3>\n

Compound (A) is precursor in this thesis for prepared new heterocyclic derivative<\/span><\/h3>\n

Compound (B) was prepared by the reaction of hydrazine hydrate 80% with<\/span><\/h3>\n

4H,4’H-[2,2′-bibenzo[d][1,3]oxazine]-4,4′-dione. This compound contain free amine group. Compound (B) was reacted with some benzaldehyde derivatives for prepared of some new Schiff bases (P,G,H,I,D,E,X<\/span><\/h3>\n

Some new cyclic amide compounds were synthesized by reacted of\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 3,3-diamino-[2,2′-biquinazoline]-4,4′(3H,3’H)-dione\u00a0 with malic or phthalic anhydride<\/span><\/h3>\n

Some new di sulfonamide compounds were prepared by the reaction of (A) with sulfathiazole or sulfadiazine for production of compounds<\/span><\/h3>\n

4,4-(4,4-dioxo-2,2′-biquinazoline -3,3′(4H,4’H)-diyl )bis (N-(thiazol-2-yl ) benzenesulfonamide (M)<\/span><\/h3>\n

4,4-(4,4-dioxo-2,2′-biquinazoline-3,3′(4H,4’H)-diyl)bis(N-(pyrimidin-2-yl) benzenesulfonamide\u00a0 (N). Compounds (M,N) have a good results against\u00a0 some bacterias\u00a0<\/span><\/h3>\n

Some aniline derivative was reacted with compound (A) for prepared some new di quinazoline (W,Z)<\/span><\/h3>\n

In this part compounds (Q,R,T,L) was prepared by the reaction of some heterocyclic compounds contain free amino group (furan-2-carbohydrazide,\u00a0\u00a0\u00a0\u00a0\u00a0 3-amino-2-phenylquinazolin-4(3H)-one ,2-amino benzothazol) and thiosemicarbazid.<\/span><\/h3>\n

Final part contain synthesis of some chalcones by the reaction of\u00a0 p-amino acetophenone with benzaldehyde derivatives for prepared of compound (K2,K3,K5,K6). All chalcones were reacted with (4H,4’H-[2,2′-bibenzo[d][1,3]oxazine]-4,4′-dione) for prepared compounds (AK2, AK3, AK5, AK6)<\/span><\/h3>\n

All synthesized compounds were test against bacterias (Staphylococcus\u00a0 aureus<\/span><\/h3>\n

\u00a0 (,Bacillus subtilis and Escherichia Coli Pseudomonas aeruginosa<\/span><\/h3>\n

All results were listed in table 3-6<\/span><\/h3>\n

 <\/p>\n

.<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"

\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 ( \u062a\u062d\u0636\u064a\u0631 \u0648\u062a\u0634\u062e\u064a\u0635 \u0628\u0639\u0636 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u062d\u0644\u0642\u064a\u0629 \u063a\u064a\u0631….<\/i>\u0627\u0644\u0645\u0632\u064a\u062f<\/span><\/a><\/p>\n","protected":false},"author":25,"featured_media":28319,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[7,16],"tags":[23],"class_list":["post-28318","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","category-16","tag-ihcoedu"],"modified_by":"ihcoedu","_links":{"self":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/28318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=28318"}],"version-history":[{"count":0,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/28318\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/28319"}],"wp:attachment":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=28318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=28318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=28318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}