{"id":28463,"date":"2019-11-26T20:47:40","date_gmt":"2019-11-26T17:47:40","guid":{"rendered":"http:\/\/ihcoedu.uobaghdad.edu.iq\/?p=28463"},"modified":"2019-11-27T09:51:46","modified_gmt":"2019-11-27T06:51:46","slug":"%d9%82%d8%b3%d9%85-%d8%a7%d9%84%d9%83%d9%8a%d9%85%d9%8a%d8%a7%d8%a1-%d9%8a%d9%86%d8%a7%d9%82%d8%b4-%d8%a7%d8%b7%d8%b1%d9%88%d8%ad%d8%a9-%d8%af%d9%83%d8%aa%d9%88%d8%b1%d8%a7%d9%87-%d8%aa%d8%a8%d8%ad-4","status":"publish","type":"post","link":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=28463","title":{"rendered":"\u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u064a\u0646\u0627\u0642\u0634 \u0627\u0637\u0631\u0648\u062d\u0629 \u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u062a\u0628\u062d\u062b \u0641\u064a \u0644\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0627\u0644\u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629 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https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2019\/11\/DSC_0742-300x200.jpg 300w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2019\/11\/DSC_0742-768x512.jpg 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0648\u0646\u0648\u0642\u0634\u062a \u0627\u0644\u0627\u0637\u0631\u0648\u062d\u0629 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0633\u0627\u062f\u0629 \u0627\u0639\u0636\u0627\u0621 \u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629 :<\/span><\/h4>\n<ul style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\">\u0623.\u062f.\u0639\u0628\u062f \u0627\u0644\u0644\u0647 \u0645\u062d\u0645\u062f \u0639\u0644\u064a\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u0631\u0626\u064a\u0633\u0627<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0623.\u062f.\u062d\u0633\u0646 \u0627\u062d\u0645\u062f 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\u00a0\u0648\u0644\u0643\u0646 \u0628\u0627\u0633\u062a\u0639\u0645\u0627\u0644 4\u061b4 \u062f\u0627\u064a \u0645\u062b\u064a\u0644 \u0627\u0645\u064a\u0646\u0648 \u0628\u0646\u0632\u0627\u0644\u062f\u064a\u0647\u0627\u064a\u062f \u0648\u0645\u064a\u062a\u0627-\u0646\u0627\u064a\u062a\u0631\u0648 \u0627\u0646\u064a\u0644\u064a\u0646. \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0633\u064a\u0644\u064a\u0646\u0648\u0633\u064a\u0645\u064a\u0643\u0627\u0631\u0628\u0632\u0648\u0646 \u0627\u0644\u0633\u062a\u0629 \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0645\u0634\u062a\u0642\u0627\u062a \u0627\u0639\u0644\u0627\u0647 \u0645\u0639 KSeCN \u0648 \u00a0NH2NH2 \u0628\u0646\u0633\u0628\u0629 1:1:3: \u0641\u064a \u0645\u0632\u064a\u062c CHCl3:EtOH (1:3) \u0643\u0645\u0630\u064a\u0628. \u062a\u0645 \u062a\u062d\u0636\u064a\u0631 \u0633\u062a\u0629 \u0648\u062b\u0644\u0627\u062b\u0648\u0646 \u0645\u0639\u0642\u062f \u062c\u062f\u064a\u062f \u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u0639 \u0627\u0645\u0644\u0627\u062d \u0627\u0644\u0641\u0644\u0632\u0627\u062a \u0628\u0646\u0633\u0628\u0629 2:1 \u0628\u0648\u062c\u0648\u062f KOH \u0643\u0642\u0627\u0639\u062f\u0629 \u0641\u064a \u0645\u0632\u064a\u062c \u0645\u0646 \u0627\u0644\u0627\u064a\u062b\u0627\u0646\u0648\u0644 \u0648\u0627\u0644\u0643\u0644\u0648\u0641\u0648\u0631\u0645 \u0628\u0646\u0633\u0628\u0629 1:3<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u0641\u0635\u0644 \u0627\u0644\u062b\u0627\u0644\u062b (\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629) \u0639\u0631\u0636 \u0648\u062a\u062d\u0644\u064a\u0644 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062a\u062d\u0627\u0644\u064a\u0644 \u0627\u0644\u0637\u064a\u0641\u064a\u0629 (\u0627\u0644\u0627\u0634\u0639\u0629 \u062a\u062d\u062a \u0627\u0644\u062d\u0645\u0631\u0627\u0621\u060c \u0627\u0644\u0627\u0634\u0639\u0629 \u0641\u0648\u0642 \u0627\u0644\u0628\u0646\u0641\u0633\u062c\u064a\u0629\u060c \u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a \u0644\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0648\u0627\u0644\u0643\u0627\u0631\u0628\u0648\u0646 \u0648\u0627\u0644\u0633\u064a\u0644\u064a\u0646\u064a\u0648\u0645 \u0648\u0637\u064a\u0641 \u0627\u0644\u0643\u062a\u0644\u0629) \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0628\u0646\u064a\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0644\u0644\u0645\u0634\u062a\u0642\u0627\u062a \u0648\u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629. \u0643\u0630\u0644\u0643 \u0627\u0634\u062a\u0645\u0644\u062a \u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062f\u0642\u064a\u0642 \u0644\u0644\u0639\u0646\u0627\u0635\u0631 (C.H.N)\u060c \u0627\u0644\u0627\u0645\u062a\u0635\u0627\u0635 \u0627\u0644\u0630\u0631\u064a \u0644\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u0641\u0644\u0632\u064a\u0629\u060c \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062d\u0631\u0627\u0631\u064a\u060c \u0645\u062d\u062a\u0648\u0649 \u0627\u0644\u0643\u0644\u0648\u0631\u060c \u0627\u0644\u062a\u0648\u0635\u064a\u0644\u064a\u0629 \u0627\u0644\u0645\u0648\u0644\u0627\u0631\u064a\u0629\u060c \u0646\u0642\u0637\u0629 \u0627\u0644\u0627\u0646\u0635\u0647\u0627\u0631 \u0648\u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a\u0629.<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u00a0\u0627\u062b\u0628\u062a\u062a \u0627\u0644\u0627\u0632\u0627\u062d\u0629 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u0629 \u0644\u0637\u064a\u0641 \u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a \u0644\u0644\u0633\u064a\u0644\u064a\u0646\u0648\u0645 \u0648\u062c\u0648\u062f \u0630\u0631\u0629 \u0627\u0644\u0633\u064a\u0644\u064a\u0646\u0648\u0645 \u0641\u064a \u0627\u0644\u0645\u0631\u0643\u0628 \u0627\u0644\u0639\u0636\u0648\u064a \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629. \u0628\u0627\u0644\u0627\u0636\u0627\u0641\u0629 \u0644\u0638\u0647\u0648\u0631 \u0627\u0634\u0627\u0631\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0637\u064a\u0641 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u062f\u0627\u064a\u0627\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a\u0629 \u0645\u0624\u0643\u062f\u0629 \u0646\u0642\u0627\u0648\u062a\u0647\u0627 \u0645\u0646 \u062c\u0647\u0629 \u0648\u0648\u062c\u0648\u062f\u0647\u0627 \u0643\u0627\u064a\u0632\u0648\u0645\u0631 \u0648\u0627\u062d\u062f \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0630\u0631\u0629 \u0627\u0644\u0645\u0631\u0643\u0632\u064a\u0629. \u0627\u062b\u0628\u062a\u062a \u0646\u062a\u0627\u0626\u062c \u0637\u064a\u0641 \u0627\u0644\u0643\u062a\u0644\u0629 \u0644\u0644\u0645\u0634\u062a\u0642\u0627\u062a \u0648 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0628\u0639\u0636 \u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0627\u0644\u0648\u0632\u0646 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629. \u0627\u0643\u062f \u0637\u064a\u0641 \u0627\u0644\u0627\u0634\u0639\u0629 \u062a\u062d\u062a \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0627\u0646 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0647\u064a \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u0633\u0646 \u0648\u062a\u0631\u062a\u0628\u0637 \u0628\u0634\u0643\u0644 \u0627\u0646\u064a\u0648\u0646 (-1) \u0645\u0639 \u0630\u0631\u0629 \u0627\u0644\u0639\u0646\u0635\u0631 \u0627\u0644\u0645\u0631\u0643\u0632\u064a\u0629. \u062a\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062d\u0631\u0627\u0631\u064a \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0628\u0639\u0636 \u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0627\u0633\u062a\u0642\u0631\u0627\u0631\u064a\u0629 \u0627\u0644\u062d\u0631\u0627\u0631\u064a\u0629 \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0641\u064a \u062f\u0631\u062c\u0627\u062a \u062d\u0631\u0627\u0631\u0629 \u0645\u062e\u062a\u0644\u0641\u0629 \u0648\u0627\u0633\u0644\u0648\u0628 \u0627\u0644\u062a\u0634\u0638\u064a.<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u062a\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0637\u064a\u0641 \u0627\u0644\u0627\u0634\u0639\u0629 \u0641\u0648\u0642 \u0627\u0644\u0628\u0646\u0641\u0633\u062c\u064a\u0629 \u0644\u0628\u064a\u0627\u0646 \u062a\u0631\u062a\u064a\u0628 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u062d\u0648\u0644 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0648\u0627\u0644\u0634\u0643\u0644 \u0627\u0644\u0641\u0631\u0627\u063a\u064a \u0627\u0644\u0645\u062a\u0648\u0642\u0639. \u0628\u064a\u0646\u062a \u0627\u0644\u062a\u0648\u0635\u064a\u0644\u064a\u0629 \u0627\u0644\u0645\u0648\u0644\u0627\u0631\u064a\u0629 \u0644\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0628\u0627\u0646\u0647\u0627 \u062a\u0633\u0644\u0643 \u0633\u0644\u0648\u0643 \u0627\u0644\u0627\u0644\u0643\u062a\u0631\u0648\u0644\u064a\u062a\u064a \u0628\u0646\u0633\u0628\u0629 2:1 \u0648\u063a\u064a\u0631 \u0627\u0644\u0627\u0644\u0643\u062a\u0631\u0648\u0644\u064a\u062a\u064a (\u0645\u062a\u0639\u0627\u062f\u0644).<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u00a0\u062a\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0628\u0631\u0646\u0627\u0645\u062c 3D Chem 16 \u0627\u0644\u0646\u0638\u0631\u064a \u0644\u0627\u062b\u0628\u0627\u062a \u0646\u0648\u0639 \u0627\u0644\u062a\u0646\u0627\u0633\u0642 \u0648\u0627\u0644\u0634\u0643\u0644 \u0627\u0644\u0647\u0646\u062f\u0633\u064a \u0627\u0644\u0645\u0641\u0636\u0644 \u062d\u0648\u0644 \u0627\u0644\u0630\u0631\u0629 \u0627\u0644\u0645\u0631\u0643\u0632\u064a\u0629 \u0641\u064a \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0648\u062a\u0645 \u0645\u0642\u0627\u0631\u0646\u0629 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0639 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u062d\u0635\u0648\u0644 \u0639\u0644\u064a\u0647\u0627 \u0645\u0646 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0644\u0637\u0631\u0642 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a\u0629 \u0644\u0644\u0645\u0639\u0642\u062f\u0627\u062a.<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0627\u0633\u062a\u0646\u0627\u062f\u0627 \u0627\u0644\u0649 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0639\u0644\u0627\u0647 \u0641\u0627\u0646 \u0646\u0648\u0639 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0648\u0627\u0644\u0634\u0643\u0644 \u0627\u0644\u0641\u0631\u0627\u063a\u064a \u0627\u0644\u0645\u0642\u062a\u0631\u062d \u0644\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u064a\u0643\u0648\u0646 \u0643\u0627\u0644\u0627\u062a\u064a:<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0645\u0639\u0642\u062f\u0627\u062a Mn(II), Co(II), Ni(II) \u0645\u0639 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL6) \u0627\u0644\u062a\u064a \u0627\u0638\u0647\u0631\u062a \u062a\u0646\u0627\u0633\u0642 \u0633\u062f\u0627\u0633\u064a \u0648\u0627\u0644\u0634\u0643\u0644 \u0647\u0648 \u062b\u0645\u0627\u0646\u064a \u0627\u0644\u0633\u0637\u0648\u062d\u060c \u0627\u0645\u0627 \u0645\u0639\u0642\u062f\u0627\u062a \u00a0(Zn(II) Cd(II))\u0648Cu(II) \u0645\u0639 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL6) \u0641\u0627\u0644\u062a\u0646\u0627\u0633\u0642 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0643\u0627\u0646 \u0631\u0628\u0627\u0639\u064a \u0627\u0644\u062a\u0646\u0627\u0633\u0642 \u0648\u0627\u0644\u0645\u0631\u0628\u0639 \u0627\u0644\u0645\u0633\u062a\u0648\u064a \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a.<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u062a\u0645 \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0628\u0627\u064a\u0644\u0648\u062c\u064a\u0629 \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0636\u062f \u0627\u0631\u0628\u0639\u0629 \u0627\u0646\u0648\u0627\u0639 \u0645\u0646 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0648\u0627\u0631\u0628\u0639 \u0627\u0646\u0648\u0627\u0639 \u0645\u0646 \u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a. \u0634\u0645\u0644\u062a \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627:<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">(E. coli, St. aureus, B. stubtilis and Klebsiella Pneumoniae)<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0627\u0645\u0627 \u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u0636\u064a\u0629\u00a0 \u0641\u0643\u0627\u0646\u062a:<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u00a0(Candida albicans, Candida glabrata, Candida tropicalis and Candida parapsilsis).<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0648\u0642\u062f \u0628\u064a\u0646\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0627 \u064a\u0644\u064a:<\/span><\/h4>\n<ul style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\">\u0627\u0638\u0647\u0631\u062a \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL6) \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0641\u0639\u0627\u0644\u064a\u0629 \u0628\u0627\u064a\u0644\u0648\u062c\u064a\u0629 \u0636\u062f<\/span><\/h4>\n<\/li>\n<\/ul>\n<ol style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\">E. coli strains.\u0648 Bacillus subtilis strains<\/span><\/h4>\n<\/li>\n<\/ol>\n<ul style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0628\u064a\u0646 \u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644 Mn(II), Ni(II) and Cu(II) \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a HL1 \u0648 HL3 \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u062a\u062c\u0627\u0647 Staphylococcus aureus strains . \u0648 Klebsiella Pneumoniae strains.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u064a\u0638\u0647\u0631 \u0644\u064a\u0643\u0627\u0646\u062f HL1 \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0636\u062f Staphylococcus aureus and Klebsiella Pneumoniae strains. . \u0643\u0630\u0644\u0643 \u0644\u0645 \u064a\u0628\u064a\u0646 \u0644\u064a\u0643\u0627\u0646\u062f HL3 \u0627\u064a \u0646\u0634\u0627\u0637 \u0636\u062f Staphylococcus aureus strain.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0627\u0638\u0647\u0631 \u0645\u0639\u0642\u062f \u0627\u0644\u0632\u0646\u0643 \u0645\u0639 \u0644\u064a\u0643\u0627\u0646\u062f HL6 \u0636\u062f coli strains. \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0628\u0642\u064a\u0629 \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0648\u062d\u0638 \u0646\u0634\u0627\u0637 \u0628\u0627\u064a\u0644\u0648\u062c\u064a \u0639\u0627\u0644\u064a \u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0632\u0646\u0643 \u0648\u0627\u0644\u0643\u0627\u062f\u0645\u064a\u0648\u0645 \u0645\u0639 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL6) \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0628\u0642\u064a\u0629 \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0648\u0627\u0644\u0633\u0628\u0628 \u064a\u0639\u0648\u062f \u0644\u0644\u062a\u0631\u062a\u064a\u0628 \u0627\u0644\u0627\u0644\u0643\u062a\u0631\u0648\u0646\u064a \u0644\u0647\u0627 (d10 ( .<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0627\u0638\u0647\u0631\u062a \u062c\u0645\u064a\u0639 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL6) \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0641\u0639\u0627\u0644\u064a\u0629 \u0636\u062f Candida glabrata.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0638\u0647\u0631 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL5) \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0636\u062f Candida parapsilsis .<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0638\u0647\u0631 \u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f HL1 \u0641\u0639\u0627\u0644\u064a\u0629 \u0636\u062f Candida parapsilsis. <\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0628\u064a\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a (HL1-HL3) \u0648\u0645\u0639\u0642\u062f\u0627\u062a Ni(II), Cd(II) \u0644\u0644\u064a\u0643\u0627\u0646\u062f HL1 \u0648\u0645\u0639\u0642\u062f \u0627\u0644\u0643\u0627\u062f\u0645\u064a\u0648\u0645 \u0644\u0644\u064a\u0643\u0627\u0646\u062f HL4 \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0636\u062f Candida albican.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u062a\u064a \u0641\u062d\u0635\u062a \u0636\u062f Candida tropicalis \u0643\u0627\u0646\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0643\u0645\u0627 \u064a\u0644\u064a:<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0638\u0647\u0631 \u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0646\u064a\u0643\u0644 \u0648\u0627\u0644\u0643\u0627\u062f\u0645\u064a\u0648\u0645 \u0645\u0639 \u0644\u064a\u0643\u0627\u0646\u062f HL1 \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0628\u0627\u064a\u0644\u0648\u062c\u064a\u0629.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u062a\u0633\u062c\u0644 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 2HL \u0648 HL3 \u0627\u064a \u0641\u0639\u0627\u0644\u064a\u0629 \u0628\u0627\u064a\u0644\u0648\u062c\u064a\u0629.\u00a0<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0644\u0645 \u064a\u0644\u0627\u062d\u0638 \u0627\u064a \u0646\u0634\u0627\u0637 \u0644\u0645\u0639\u0642\u062f \u0627\u0644\u0646\u064a\u0643\u0644 \u0645\u0639 \u0644\u064a\u0643\u0627\u0646\u062f HL4.<\/span><\/h4>\n<\/li>\n<li>\n<h3><span style=\"color: #000080\">\u0627\u0638\u0647\u0631\u062a \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a HL5 \u0648 HL6 \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0645\u0627 \u0646\u0634\u0627\u0637 \u0628\u0627\u064a\u0644\u0648\u062c\u064a \u0639\u0627\u0644\u064a \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0628\u0627\u0642\u064a \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a.<\/span><\/h3>\n<hr \/>\n<\/li>\n<\/ul>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Metal Complexes Derived From Polydentate \u00a0\u00a0\u00a0\u00a0Ligands; Synthesis, Spectral Characterization<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">And Biological Activity<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">By Talib Hamid Mawat<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Supervised by prof.Dr. Mohammed Jabir Ibrahim<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Summary<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 This thesis is based on the synthesis, spectral characterization, thermal investigation and biological activity of six novel selenosemicarbazone ligands, which derived from Mannich reaction, and their metal complexes. The aim of using selenosemicarbazone compounds is based on the role and applications of Se-based compounds in inorganic chemistry, medicine, pharmaceutical industry, analytical chemistry and biological activity. Further checking on reported data in literature, there is a limited published work on this type of ligands and their complexes Therefore, this fact encouraged us to investigate such compounds and to the best of our knowledge this is the first thesis in Iraq dealing with the synthesis of selenosemicarbazone ligands and their complexes. This thesis consists of four chapters in which;<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">The first chapter gives an introduction on Mannich-reaction approach and a literature review covering the development of the formation of metal complexes with N, Se coordination core. These include macrocyclic and non-macrocyclic ligands with their metal complexes. Moreover, applications and uses these compounds with their references were mentioned in the introduction along with the aim of the work.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">The second chapter covers the experimental part that include materials used in this work, analytical techniques and synthetic procedures used to prepare organic precursors, selenosemicarbazone ligands and their metal complexes. Ligands were prepared in a multi synthetic steps, which divided into a two set depending on type of precursor that used in the formation of ligands. The first set of precursors F1, F2 and F3 were obtained using a one-pot Mannich-reaction. The condensation reaction of benzaldehyde, methoxybenzaldehyde and 4,4`-dimethylaminobenzaldehyde with cyclohexanone and ammonium acetate in a 2:1:1 mole ratio in EtOH medium resulted in the isolation of F1, F2 and F3, respectively. The second set of precursors is based on the preparation of N1, N2 and N3 adopting Mannich-approach by mixing calcium chloride and the title aldehyde and aromatic amine with cyclohexanone and in a 1:1:1:1 mole ratio in EtOHsolvent (benzaldehyde and m-nitroaniline for N1; 4-methoxybenzaldehyde and aniline for N2, and N3was prepared by analogous procedure to that for N1 but with the use of 4,4`-dimethylaminobenzaldehyde and m-nitroaniline for N3).<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">The six novel selenosemicarbazone ligands HL1-HL6 were synthesised from the reaction of the title precursor with KSeCN and NH2NH2 in a 1:1:3 mole ratio in a mixture of CHCl3:EtOH (1:3) as a solvent. A total of thirtysix complexes were synthesised from the reaction of ligands with metal chloride salts in a 2:1 L:M mole ratio,in presence of KOH as a base, using a mixture of chloroform\/ethanol (1:3) as a reaction medium (see Scheme).<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">The third chapter (results and discussion) deals with presenting and discussion of the analytical and spectroscopic data that used to conclude the entity of precursors, selenosemicarbazone ligands and their metal complexes. These include the use of; elemental analysis (CHN), atomic absorption (A.A), thermal analysis, chloride ratio, conductance, melting point, FT-IR, UV-Vis, magnetic susceptibility, 1H-, 13C- and 77Se-NMR and ESMS (electrospray mass spectra). The chemical shift of the 77Se-NMR confirmed the incorporation of the Se-atom in the organic segment and the isolation of the selenosemicarbazone ligands and their metal complexes. Further, the presence of one signal in the spectral data of ligands and their diamagnetic complexes indicated the purity, the isolation of one isomer and that the two bound ligands of diamagnetic complexes are equivalents. The ESMS spectroscopic of precursors, ligands and some metals complexes confirmed molecular weight of synthesized compounds. The FT-IR spectra of the complexes of ligands HL1-HL6 showed act as a bidentate and behaves as negative species (-1) upon coordination with metal ions. Thermal analysis of ligands HL1-HL6 and some metals complexes indicated stability of these compounds in the different temperatures and fragmentation. UV-Vis spectra of complexes were used to predict the arrangement of the ligand around metal ion. The molar conductivity values of complexes were included non-electrolytes and electrolytes with 2:1 ratio. Theoretical approach was used to confirm the coordination mode and the preferred geometry arrangement around metal centre. This was based on using 3D Chem 16 program and checking data against that obtained from the analytical and chemical analysis of complexes.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Based on the above analyses, the interaction behavior and mode of bonding and suggested structure of complexes is shown below:\u00a0<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Metal complexes of Mn(II), Co(II) and Ni(II) with HL1-HL6 revealed six-coordinate arrangement in which the proposed geometry about metal centre is octahedral. Complexes of Cu(II); Zn(II) and Cd(II) with HL1-HL6 revealed the isolation of four-coordinate complexes in which the proposed geometry is square planar and tetrahedral, respectively.<\/span><\/h3>\n<h3 style=\"text-align: left\"><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Scheme: Synthetic pathway of HL1-HL6and metal complexes.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Biological activities of compounds (ligands and complexes) weretested toward four strains of bacteria (E. coli, B. stubtilis, St. aureusand Klebsiella Pneumoniae)and four species of fungi (Candida albicans, Candida glabrata, Candida tropicalis and Candida parapsilsis). The following trend is observed for the tested compounds;<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL1-HL6 and their complexes displayed activity against Esherichia Coli and Bacillus subtilis strains.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Complexes of Mn(II), Ni(II) and Cu(II) with HL1 and HL3 showed no activity against Staphylococcus aureus and Klebsiella Pneumoniae strains.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligand HL1 exhibited no activity against Staphylococcus aureus and Klebsiella Pneumoniae strains. More, HL3 shows no antimicrobial activity against Staphylococcus aureusstrain.\u00a0<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Zinc complex with HL6 showed the highest antimicrobial activity against E. coli strain, compared with other complexes.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Complexes of zinc and cadmium with the examined ligands HL1-HL6indicated to be more resistance towards tested species, due to their d10 configuration.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL1-HL6 and their metal complexes showed activity against Candida glabrata.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL1-HL5 displayed no activity against Candida parapsilsis.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">All complexes of HL1 exhibited no activity against Candida parapsilsis.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL1-HL3 did not show any activity against Candida albicans.\u00a0\u00a0<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Complexes of Ni(II) and Cd(II) with HL1 and complex Cd(II) with HL4 showed no activity against Candida albicans.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Regarding the activity of tested compounds against Candida tropicalis, the following results are observed:<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Complexes of Ni(II) and Cd(II) with HL1 displayed no-activity.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL2 and HL3 showed no-activity.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Complex of Ni(II) with HL4 did not exhibit any activity.<\/span><\/h3>\n<h3 style=\"text-align: left\"><span style=\"color: #993366\">Ligands HL5 and HL6 with their metal complexes exhibited higher activity in comparison with other compounds<\/span><\/h3>\n<p style=\"text-align: left\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0627\u0637\u0631\u0648\u062d\u0629 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 ( \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0627\u0644\u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629&#8230;.<a class=\"cz_readmore\" href=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=28463\"><i class=\"fa fa-angle-left\" aria-hidden=\"true\"><\/i><span>\u0627\u0644\u0645\u0632\u064a\u062f<\/span><\/a><\/p>\n","protected":false},"author":25,"featured_media":28465,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[7,16],"tags":[23],"class_list":["post-28463","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","category-16","tag-ihcoedu"],"modified_by":"ihcoedu","_links":{"self":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/28463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=28463"}],"version-history":[{"count":0,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/28463\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/28465"}],"wp:attachment":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=28463"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=28463"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=28463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}