{"id":32402,"date":"2020-05-06T02:56:41","date_gmt":"2020-05-05T23:56:41","guid":{"rendered":"http:\/\/ihcoedu.uobaghdad.edu.iq\/?p=32402"},"modified":"2020-05-06T03:03:07","modified_gmt":"2020-05-06T00:03:07","slug":"%d9%82%d8%b3%d9%85-%d8%b9%d9%84%d9%88%d9%85-%d8%a7%d9%84%d8%ad%d9%8a%d8%a7%d8%a9-%d9%8a%d9%86%d8%a7%d9%82%d8%b4-%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1-%d8%aa-13","status":"publish","type":"post","link":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=32402","title":{"rendered":"\u0642\u0633\u0645 \u0639\u0644\u0648\u0645 \u0627\u0644\u062d\u064a\u0627\u0629 \u064a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u062a\u0628\u062d\u062b \u0641\u064a \u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u0636\u0627\u0631\u0629 \u0644\u0644\u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0627\u0644\u0645\u0632\u0645\u0646 \u0644\u0639\u0642\u0627\u0631 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src=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2020\/05\/DSC_0176.jpg\" alt=\"\" width=\"800\" height=\"533\" srcset=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2020\/05\/DSC_0176.jpg 800w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2020\/05\/DSC_0176-300x200.jpg 300w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2020\/05\/DSC_0176-768x512.jpg 768w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/strong><\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\"><strong>\u00a0<\/strong><\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\"><strong>\u0648\u062a\u0647\u062f\u0641 \u0627\u0644\u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0649 :<\/strong><\/span><\/h4>\n<ul style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\"><strong>\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0622\u062b\u0627\u0631 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<\/strong><strong>selenium <\/strong><strong>.<\/strong><\/span><\/h4>\n<\/li>\n<\/ul>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\"><strong>\u00a0<\/strong><\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u00a0\u00a0 \u0635\u064f\u0645\u0645\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0644\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0633\u0645\u064a \u0644\u0639\u0642\u0627\u0631 \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0648\u0632\u0627\u0646 \u0648 \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0641\u0633\u0644\u062c\u064a\u0629 \u0644\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u0643\u0627\u062b\u0631\u064a\u0629 ( \u0627\u0644\u062e\u0635\u0649 \u0648 \u0627\u0630\u0646\u0627\u0628 \u0627\u0644\u0628\u0631\u0627\u0628\u062e 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\u0623\u0633\u0627\u0628\u064a\u0639 .<\/span><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u00a0\u00a0 \u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0630\u0643\u0648\u0631 \u0627\u0644\u062c\u0631\u0630 \u0627\u0644\u0645\u0639\u0627\u0645\u0644\u0629 \u0628\u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 ( \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 ) \u0627\u0646\u062e\u0641\u0627\u0636\u0627\u064b \u0645\u0639\u0646\u0648\u064a\u0627\u064b (P\u22640.05) \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0639\u0627\u0644\u0645 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0627\u0639\u0644\u0627\u0647 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0646\u0638\u064a\u0631\u0629 \u0644\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 . \u0628\u064a\u0646\u0645\u0627 \u0633\u062c\u0644\u062a \u0646\u062a\u0627\u0626\u062c \u0630\u0643\u0648\u0631 \u0627\u0644\u062c\u0631\u0630 \u0627\u0644\u0645\u0639\u0627\u0645\u0644\u0629 \u0628\u0627\u0644\u0641\u064a\u062a\u0648\u0641\u0631\u062a \u0628\u0639\u062f \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0627\u0631\u062a\u0641\u0627\u0639\u0627 \u064b\u0645\u0639\u0646\u0648\u064a\u0627 \u064b(P\u22640.05) \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u060c \u0648\u0644\u0645 \u064a\u0644\u0627\u062d\u0638 \u0647\u0646\u0627\u0643 \u0623\u064a\u0629 \u0641\u0631\u0648\u0642 \u0645\u0639\u0646\u0648\u064a\u0629 (P&gt;0.05) \u0639\u0646\u062f \u0645\u0642\u0627\u0631\u0646\u062a\u0647\u0627 \u0645\u0639 \u0642\u064a\u0645 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 ( \u0627\u0644\u0633\u064a\u0637\u0631\u0629 ) . \u0648\u0644\u0645 \u064a\u0643\u0646 \u0627\u0644\u0641\u0631\u0642 \u0645\u0639\u0646\u0648\u064a\u0627\u064b (P&gt;0.05) \u0639\u0646\u062f \u0645\u0642\u0627\u0631\u0646\u0629 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u0639\u0627\u0645\u0644\u0629 \u0628\u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u062b\u0645 \u0627\u0644\u0633\u064a\u0644\u064a\u0646\u064a\u0648\u0645 ( \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0631\u0627\u0628\u0639\u0629 ) \u0645\u0639 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0646\u0638\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u060c \u0641\u064a \u062d\u064a\u0646 \u0633\u062c\u0644 \u0641\u0631\u0642 \u0645\u0639\u0646\u0648\u064a (P\u22640.05) \u0639\u0646\u062f \u0645\u0642\u0627\u0631\u0646\u062a\u0647\u0627 \u0628\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 .<\/span><\/h4>\n<h4 style=\"text-align: justify\"><\/h4>\n<h4 style=\"text-align: justify\"><span style=\"color: #000080\">\u0648\u062e\u0644\u0635\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0649 \u0627\u0644\u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u0627\u062a\u064a\u0629 :<\/span><\/h4>\n<ul style=\"text-align: justify\">\n<li>\n<h4><span style=\"color: #000080\">\u0627\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0646 \u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u062f\u0627\u062e\u0644 \u062e\u0644\u0648\u064a \u0644\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u0643\u0627\u062b\u0631\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0639\u0645\u0644\u0629 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 .<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0627\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0627\u062a \u0639\u0646 \u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0627\u0646\u0648\u0627\u0639 \u0627\u0644\u0623\u0648\u0643\u0633\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u0629 \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u0643\u0627\u062b\u0631\u064a\u0629 \u0627\u0644\u062b\u0644\u0627\u062b\u0629 .<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0627\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0629 \u0639\u0646 \u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0641\u064a \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0644\u0644\u0646\u0637\u0627\u0641.<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"color: #000080\">\u0627\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0629 \u0639\u0646 \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u062e\u0644\u0648\u064a \u0627\u0644\u0645\u0628\u0631\u0645\u062c \u0628\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0646\u0627\u0628\u0631\u0648\u0643\u0633\u064a\u0646 \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u0643\u0627\u062b\u0631\u064a\u0629 \u0627\u0644\u062b\u0644\u0627\u062b\u0629 .<\/span><\/h4>\n<\/li>\n<\/ul>\n<h4 style=\"direction: ltr;text-align: justify\"><\/h4>\n<h4 style=\"direction: ltr;text-align: justify\"><span style=\"color: #000080\">Summary<\/span><\/h4>\n<h4 style=\"direction: ltr;text-align: justify\"><span style=\"color: #000080\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 The current study was designed to verify of the toxic effect of the naproxen drug on the weights and physiological functions of the reproductive organs (testes, and caudal epididymis and the ventral lobe of the prostate (VPL) gland ) which\u00a0 included epididymal sperm parameters and some functional indicators such as testicular and epididymal ACP enzyme activity, zinc concentration, and PSA specific antigen in tissue of VPL and serum, as well as some biochemical indicators such as the total protein concentration and oxidative stress indicators, in addition the hormonal concentrations (T, LH,FSH ) in the serum and histometric and histopathological study of the mentioned reproductive organs. The current study was also done to detect protective role of the phitofert product and selenium against the toxic effect of naproxen.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n<h4 style=\"direction: ltr;text-align: justify\"><span style=\"color: #000080\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 In this study, 32 male rats were used and divided into four groups ( 8 rats each ) as follows : Group 1 (control) : male rats were treated with 1 ml\u00a0 of distilled water daily for 4 consecutive weeks. Group 2 : male rats treated with naproxen at a concentration of ( 21mg.kg-\u00b9.bw. ) for 4 consecutive weeks. Group 3 : male rats were treated with phitofert (7mg. kg-\u00b9. bw.) after 5-6 h of naproxen dosing, for 4 consecutive weeks. Group 4 : male rats treated with selenium (50 \u00b5g) after 5-6 h of naproxen dosing, for 4 consecutive weeks .\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n<h4 style=\"direction: ltr;text-align: justify\"><span style=\"color: #000080\">Results of \u00a0male rats treated with naproxen (group 2) showed a significant (P\u22640.05) decrease\u00a0 in all parameters mentioned above compared to the values \u200b\u200bof group 1. While the results of male rats treated with phitofert after naproxen (group 3) recorded a significant increase (P\u22640.05) compared to the group 2 , and no significant (P&gt;0.05)differences were observed when compared to the values \u200b\u200bof the group 1 (control). There was no significant (P&gt;0.05) differences \u00a0between the\u00a0 results\u00a0 of male rats treated with selenium after treated with naproxen (group 4) compared to those in group 2. While , there was \u00a0a significant (P\u22640.05) when compared to the results of the group 3 . These results confirmed that , the naproxen &#8211; induced negative change of \u00a0reproductive organs were due to the appearance of the oxidative stress status in tissues of these organs . Whereas, the phitofert had important role in the preventing of these negative variables according to it\u2019s a highly efficient as antioxidant substance . While selenium failed in reverse of these passive changes . This failure maybe attributed to the interaction between naproxen and selenium .\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0639\u0644\u0648\u0645 \u0627\u0644\u062d\u064a\u0627\u0629 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 ( \u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0648\u0642\u0627\u0626\u064a \u0644\u0644\u0641\u064a\u062a\u0648\u0641\u0631\u062a \u0648\u0627\u0644\u0633\u064a\u0644\u064a\u0646\u064a\u0648\u0645 \u0636\u062f&#8230;.<a class=\"cz_readmore\" href=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=32402\"><i class=\"fa fa-angle-left\" aria-hidden=\"true\"><\/i><span>\u0627\u0644\u0645\u0632\u064a\u062f<\/span><\/a><\/p>\n","protected":false},"author":25,"featured_media":32404,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[7,16],"tags":[23,48],"class_list":["post-32402","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","category-16","tag-ihcoedu","tag-bio"],"modified_by":"ihcoedu","_links":{"self":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/32402","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=32402"}],"version-history":[{"count":0,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/32402\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/32404"}],"wp:attachment":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=32402"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=32402"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=32402"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}