{"id":32466,"date":"2020-05-12T10:34:17","date_gmt":"2020-05-12T07:34:17","guid":{"rendered":"http:\/\/ihcoedu.uobaghdad.edu.iq\/?p=32466"},"modified":"2020-05-12T11:22:26","modified_gmt":"2020-05-12T08:22:26","slug":"%d9%82%d8%b3%d9%85-%d8%a7%d9%84%d9%83%d9%8a%d9%85%d9%8a%d8%a7%d8%a1-%d9%8a%d9%86%d8%a7%d9%82%d8%b4-%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1-%d8%aa%d8%a8%d8%ad%d8%ab-16","status":"publish","type":"post","link":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=32466","title":{"rendered":"\u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u064a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u062a\u0628\u062d\u062b \u0641\u064a \u062a\u062d\u0636\u064a\u0631 \u0648 \u062a\u0634\u062e\u064a\u0635 \u0645\u0639\u0642\u062f\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u0627\u0646\u062e \u0645\u0639 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0644\u0647\u0627"},"content":{"rendered":"

\"\"<\/span><\/h4>\n

\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 ( \u0645\u0639\u0642\u062f\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u0627\u0646\u062e; \u00a0\u062a\u062d\u0636\u064a\u0631 \u0648 \u062a\u0634\u062e\u064a\u0635 \u0637\u064a\u0641\u064a \u0645\u0639 \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a ) \u0644\u0644\u0637\u0627\u0644\u0628 ( \u0639\u0645\u0627\u0631 \u062d\u0633\u0646 \u0639\u0628\u062f \u0627\u0644\u0647\u0627\u062f\u064a ) \u0627\u0644\u062a\u064a \u0627\u0646\u062c\u0647\u0627 \u062a\u062d\u062a \u0627\u0634\u0631\u0627\u0641 \u0627\u0644\u062a\u062f\u0631\u064a\u0633\u064a \u0641\u064a \u0627\u0644\u0642\u0633\u0645 ( \u0623.\u062f. \u0645\u062d\u0645\u062f \u062c\u0627\u0628\u0631 \u0627\u0628\u0631\u0627\u0647\u064a\u0645 \u0627\u0644\u062c\u0628\u0648\u0631\u064a) \u060c \u0648\u0646\u0648\u0642\u0634\u062a \u0645\u0646 \u0642\u0628\u0644 \u0627\u0639\u0636\u0627\u0621 \u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0646\u0627\u0642\u0634\u0629 \u0627\u0644\u0645\u062f\u0631\u062c\u0629 \u0627\u0633\u0645\u0627\u0626\u0647\u0645 \u0641\u064a\u0645\u0627 \u064a\u0627\u062a\u064a:<\/span><\/h4>\n
    \n
  • \n

    \u0623.\u062f. \u062d\u0633\u0646 \u0623\u062d\u0645\u062f \u062d\u0633\u0646 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (\u0631\u0626\u064a\u0633\u0627)<\/span><\/h4>\n<\/li>\n
  • \n

    \u0623.\u0645.\u062f. \u0639\u064a\u062f \u0635\u0627\u0644\u062d \u0645\u062d\u0645\u062f \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (\u0639\u0636\u0648\u0627)<\/span><\/h4>\n<\/li>\n
  • \n

    \u0623.\u0645.\u062f. \u0648\u0631\u0648\u062f \u0639\u0644\u064a \u062c\u0639\u0641\u0631 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (\u0639\u0636\u0648\u0627)<\/span><\/h4>\n<\/li>\n
  • \n

    \u0623.\u062f. \u0645\u062d\u0645\u062f \u062c\u0627\u0628\u0631 \u0627\u0628\u0631\u0627\u0647\u064a\u0645 \u0627\u0644\u062c\u0628\u0648\u0631\u064a (\u0639\u0636\u0648\u0627 \u0648\u0645\u0634\u0631\u0641\u0627)<\/span><\/h4>\n<\/li>\n<\/ul>\n

    \"\"<\/p>\n

    \u0648\u064a\u0647\u062f\u0641 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0649 \u062a\u062d\u0636\u064a\u0631 :<\/span><\/h4>\n
      \n
    1. \n

      \u0644\u064a\u0643\u0627\u0646\u062f \u062b\u0646\u0627\u0626\u064a \u0627\u0644\u0633\u0646 \u0645\u0646 \u0642\u0648\u0627\u0639\u062f \u0645\u0627\u0646\u062e \u0648\u062a\u0645 \u062a\u0633\u0645\u064a\u062a\u0647 :<\/span><\/h4>\n<\/li>\n<\/ol>\n

      (2R)-2-((R)-(4(dimethylamino)phenyl)(phenylamino)methyl) 4methylcyclohexan-1-one (HL1<\/sup>)<\/span><\/h4>\n

      \u0645\u0646 \u0645\u0632\u062c \u062b\u0644\u0627\u062b \u0645\u0631\u0643\u0628\u0627\u062a \u0639\u0636\u0648\u064a\u0629 (\u0628\u0627\u0631\u0627-\u0645\u062b\u064a\u0644 \u0633\u0627\u064a\u0643\u0644\u0648\u0647\u0643\u0633\u0627\u0646\u0648\u0646 , \u0627\u0644\u0623\u0646\u0644\u064a\u0646 , \u0628\u0627\u0631\u0627 \u062b\u0646\u0627\u0626\u064a \u0645\u062b\u064a\u0644 \u0627\u0645\u064a\u0646\u0648 \u0628\u0646\u0632\u0644\u062f\u064a\u0647\u0627\u064a\u062f )<\/span><\/h4>\n
        \n
      1. \n

        \u062a\u062d\u0636\u064a\u0631 \u0642\u0627\u0639\u062f\u0629 \u0634\u064a\u0641 \u0644\u0644\u064a\u0643\u0627\u0646\u062f \u062b\u0644\u0627\u062b\u064a \u0627\u0644\u0633\u0646 \u062c\u062f\u064a\u062f \u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a \u0643\u0627\u0631\u0628\u0627\u0632\u0648\u0646 \u0648\u062a\u0645 \u062a\u0633\u0645\u064a\u062a\u0647 :<\/span><\/h4>\n<\/li>\n<\/ol>\n

        \u00a0(E)-2-((2S)-2-((S)-(4(dimethylamino)phenyl) (phenylamino)methyl))-4-methylcyclohexylidene)hydrazine-1-carbothioamide (H2<\/sub>L2<\/sup>)<\/span><\/h4>\n

        \u0645\u0646 \u0645\u0632\u062c \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u0627\u0648\u0644 \u0645\u0639 \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a \u0643\u0627\u0631\u0628\u0627\u0632\u0627\u064a\u062f<\/span><\/h4>\n
          \n
        1. \n

          \u062a\u062d\u0636\u064a\u0631 \u0633\u0644\u0633\u0644\u0629 \u0645\u0639\u0642\u062f\u0627\u062a \u0644\u0643\u0644\u0627 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 \u0645\u0639 \u0627\u064a\u0648\u0627\u0646\u0627\u062a Mn(II)<\/sup>, Co(II)<\/sup>, Ni(II)<\/sup>,\u00a0 Cu(II)<\/sup>,\u00a0 Zn(II)<\/sup>\u00a0\u00a0 Cd(II)<\/sup>,<\/span><\/h4>\n<\/li>\n
        2. \n

          \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0628 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0648\u0627\u0644\u0627\u0634\u0643\u0627\u0644 \u0627\u0644\u0641\u0631\u0627\u063a\u064a\u0629 \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0645\u062d\u0636\u0631\u0629<\/span><\/h4>\n<\/li>\n
        3. \n

          \u0627\u0633\u062a\u0643\u0634\u0627\u0641 \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0644\u0643\u0644\u0627 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0636\u062f \u0633\u0644\u0627\u0644\u0627\u062a G + \u0648 G- \u0645\u0646 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u0648\u0646\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a.<\/span><\/h4>\n<\/li>\n<\/ol>\n

          <\/h4>\n

          \u062a\u0634\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u062a\u062d\u0636\u064a\u0631 \u0648\u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0647\u064a\u0643\u0644\u064a \u0648\u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0644\u0646\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u0639 \u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629. \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u0627\u0648\u0644 \u064a\u0633\u0645\u0649 :<\/span><\/h4>\n

          (2R)-2-((R)-(4(dimethylamino)phenyl)(phenylamino)methyl)-4-methyl cyclohexan-1-one (HL1<\/sup>)<\/span><\/h4>\n

          \u0648 \u0642\u062f \u062a\u0645 \u062a\u062d\u0636\u064a\u0631\u0647 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0627\u062d\u0627\u062f\u064a \u0645\u0634\u062a\u0642 \u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0645\u0627\u0646\u062e \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0643\u0644\u0648\u0631\u064a\u062f \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645 \u0643\u0645\u062d\u0641\u0632. \u0627\u062c\u0631\u0627\u0621 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u062a\u0645 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0643\u062d\u0648\u0644 \u0627\u0644\u0627\u062b\u064a\u0644\u064a \u0643\u0648\u0633\u0637 \u0644\u0644\u062a\u0641\u0627\u0639\u0644 \u0648\u0645\u0646 \u062e\u0644\u0627\u0644 \u0645\u0632\u062c \u062b\u0644\u0627\u062b \u0645\u0643\u0648\u0646\u0627\u062a \u0647\u064a : \u0628\u0627\u0631\u0627-\u062b\u0646\u0627\u0626\u064a-\u0645\u062b\u064a\u0644-\u0627\u0645\u064a\u0646\u0648 \u0628\u0646\u0632\u0644\u062f\u064a\u0647\u0627\u064a\u062f , \u0627\u0644\u0627\u0646\u0644\u064a\u0646 \u0648 \u0628\u0627\u0631\u0627-\u0645\u062b\u064a\u0644 \u0633\u0627\u064a\u0643\u0644\u0648\u0647\u0643\u0633\u0627\u0646\u0648\u0646 \u0628\u0646\u0633\u0628\u0629 \u0645\u0648\u0644\u064a\u0629 \u0645\u0642\u062f\u0627\u0631\u0647\u0627 1:1:1, \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a , \u062a\u0645 \u062a\u062d\u0631\u064a\u0643 \u0627\u0644\u0645\u0632\u064a\u062c \u0644\u0645\u062f\u0629 12 \u0633\u0627\u0639\u0629 \u0639\u0646\u062f \u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u063a\u0631\u0641\u0629. \u062a\u0645 \u0627\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0627\u0644\u0646\u0627\u062a\u062c \u0627\u0644\u0645\u0637\u0644\u0648\u0628 \u0643\u0645\u0627\u062f\u0629 \u0635\u0644\u0628\u0629 \u062b\u0645 \u062a\u0631\u0634\u064a\u062d\u0647\u0627 \u0648\u063a\u0633\u0644\u0647\u0627 \u0628\u0627\u0644\u0645\u0627\u0621 \u0627\u0644\u0645\u0642\u0637\u0631\u0648\u0627\u0639\u0627\u062f\u0629 \u0628\u0644\u0648\u0631\u062a\u0647\u0627 \u0648\u062a\u062c\u0641\u064a\u0641\u0647\u0627 .\u0631\u0627\u062c\u0639 \u0627\u0644\u0645\u062e\u0637\u0637( \u0623 ).<\/span><\/h4>\n

          \u0648\u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u062b\u0627\u0646\u064a :\u00a0<\/span>(E)-2-((2S)-2-((S)-(4(dimethylamino)phenyl) (phenylamino)methyl)-4-methyl cyclohexylidene)hydrazine-1carbothioamide (H2<\/sub>L2<\/sup>).<\/span><\/h4>\n

          \u062a\u0645 \u062a\u0627\u0643\u064a\u062f \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f (H2<\/sub>L2<\/sup>) \u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u062a\u0643\u062b\u064a\u0641 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0643\u064a\u062a\u0648\u0646 \u0645\u0639 \u0645\u0631\u0643\u0628 \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a \u0643\u0627\u0631\u0628\u0627\u0632\u0627\u064a\u062f \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u062a\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 HL1<\/sup> \u0643\u0645\u0627\u062f\u0629 \u0627\u0648\u0644\u064a\u0629 \u062a\u0648\u0641\u0631 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0643\u0627\u0631\u0628\u0648\u0646\u064a\u0644 \u0648\u0627\u0644\u062a\u064a \u062a\u062a\u0641\u0627\u0639\u0644 \u0645\u0639 \u0627\u0645\u064a\u0646 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0647\u064a\u062f\u0631\u0627\u0632\u064a\u0646\u064a \u0645\u0646 \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a \u0643\u0627\u0631\u0628\u0627\u0632\u0627\u064a\u062f. \u062a\u0645 \u062a\u062d\u0636\u064a\u0631(H2<\/sub>L2<\/sup>) \u0645\u0646 \u0627\u0636\u0627\u0641\u0629 \u0645\u0627 \u064a\u0639\u0627\u062f\u0644 \u0645\u0643\u0627\u0641\u0649 \u0648\u0627\u062d\u062f \u0645\u0646 \u0645\u062d\u0644\u0648\u0644 \u0627\u0644\u0627\u064a\u062b\u0627\u0646\u0648\u0644\u064a \u0645\u0646 \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a \u0643\u0627\u0631\u0628\u0627\u0632\u0627\u064a\u062f \u0627\u0644\u0649 \u0646\u0633\u0628\u0629 \u0645\u0643\u0627\u0641\u0649 \u0644\u0644\u064a\u0643\u0627\u0646\u062f HL1<\/sup> \u0644\u0623\u0639\u0637\u0627\u0621 (H2<\/sub>L2<\/sup>) \u0628\u0643\u0645\u064a\u0629 \u0645\u0639\u062a\u062f\u0644\u0629. \u062a\u0645 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0644\u0645\u062f\u0629 5 \u0633\u0627\u0639\u0627\u062a \u0628\u0648\u0627\u0633\u0637\u0629 \u0627\u0644\u062a\u0635\u0639\u064a\u062f \u0627\u0644\u0639\u0643\u0633\u064a\u00a0 \u0648\u062a\u0645 \u062a\u0631\u0634\u064a\u062d \u0627\u0644\u0646\u0627\u062a\u062c \u0627\u0644\u0635\u0644\u0628 \u0648\u063a\u0633\u0644\u0647 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0627\u064a\u062b\u0627\u0646\u0648\u0644 \u0648\u0627\u0644\u0627\u064a\u062b\u0631, \u0627\u0646\u0638\u0631 \u0627\u0644\u0645\u062e\u0637\u0637 (\u0628).<\/span><\/h4>\n

          \"\"<\/h4>\n

          \u0627\u0644\u0645\u062e\u0637\u0637\u00a0 (\u0623) : \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0644\u062a\u062d\u0636\u064a\u0631\u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u0627\u0648\u0644 HL1<\/sup>.<\/span><\/h4>\n

          \"\"\u0627\u0644\u0645\u062e\u0637\u0637 (\u0628) : \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0644\u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u062b\u0627\u0646\u064a H2<\/sub>L2<\/sup>.<\/span><\/h4>\n

          <\/h4>\n

          \u062a\u0645 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0643\u0644\u0627 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 \u0627\u0644\u0645\u062d\u0636\u0631\u064a\u0646\u00a0 \u0644\u062a\u062d\u0636\u064a\u0631 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0645\u0639 \u0627\u064a\u0648\u0646\u0627\u062a :<\/span><\/h4>\n

          \u00a0Mn(II)<\/sup>, Co(II)<\/sup>, Ni(II)<\/sup>, Cu(II)<\/sup>, Zn(II)<\/sup>\u00a0 and Cd(II)<\/sup><\/span><\/h4>\n

          \u0641\u064a \u0646\u0633\u0628\u0629 2:1 (\u0641\u0644\u0632:\u0644\u064a\u0643\u0627\u0646\u062f) \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0627\u064a\u062b\u0627\u0646\u0648\u0644 \u0627\u0648 DMF \u00a0\u0643\u0645\u0630\u064a\u0628. \u062a\u0645 \u062a\u062d\u0631\u064a\u0643 \u0627\u0644\u0645\u0632\u064a\u062c \u0644\u0645\u062f\u0629 24 \u0633\u0627\u0639\u0629 \u0628\u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u063a\u0631\u0641\u0629. \u062a\u0645 \u0627\u0644\u0633\u0645\u0627\u062d \u0644\u0644\u0645\u062d\u0644\u0648\u0644 \u0628\u0627\u0644\u062a\u0628\u062e\u0631 \u0628\u0628\u0637\u0621 \u0639\u0646\u062f \u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u063a\u0631\u0641\u0629 , \u0648\u062a\u0645 \u062a\u0643\u0648\u064a\u0646 \u0645\u0633\u062d\u0648\u0642 \u0635\u0644\u0628 \u0648\u0627\u0644\u0630\u064a \u062a\u0645 \u062a\u0631\u0634\u064a\u062d\u0647 \u0648\u063a\u0633\u0644\u0647 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0643\u0644\u0648\u0631\u0648\u0641\u0648\u0631\u0645 \u0648\u0627\u0644\u0627\u064a\u062b\u0631, \u0627\u0646\u0638\u0631 \u0644\u0644\u0645\u062e\u0637\u0637 \u062c. \u0627\u0639\u0637\u0649 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u0627\u0648\u0644 \u00a0HL1<\/sup> \u0645\u0639\u0642\u062f\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u0645\u0648\u0646\u0645\u0631\u064a\u0629 \u0644\u0644\u0635\u064a\u063a\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 :<\/span><\/h4>\n

          [Mn(HL1<\/sup>)2<\/sub>(Cl)2<\/sub>],\u00a0<\/span>\u00a0[M(HL1<\/sup>)2<\/sub>(Cl)2<\/sub>](H2<\/sub>O) (where M= Co(II)<\/sup>, Ni(II)<\/sup>, Cu(II)<\/sup> ,\u00a0<\/span>\u00a0[Zn(HL1<\/sup>)](H2<\/sub>O) Cl2<\/sub> and [Cd(HL1<\/sup>)] Cl2<\/sub><\/span><\/h4>\n

          \u0623\u0639\u0637\u0649 (H2<\/sub>L2<\/sup>)\u00a0 \u0627\u0644\u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0628\u0648\u0644\u064a\u0645\u0631\u064a\u0629 \u0639\u0646\u062f \u062a\u0641\u0627\u0639\u0644\u0647 \u0645\u0639 \u0627\u0644\u0627\u064a\u0648\u0646\u0627\u062a \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0622\u0646\u0641\u0627\u064e \u0630\u0627\u062a \u0635\u064a\u063a\u0629 \u0639\u0627\u0645\u0629:<\/span><\/h4>\n

          {[M(HL2<\/sup>)]Cl2<\/sub>}n (where M= Mn(II)<\/sup>, Co(II)<\/sup>, Ni(II)<\/sup>, Cu(II)<\/sup>, Zn(II)<\/sup>, Cd(II)<\/sup>)<\/span><\/h4>\n

          \u0627\u0646\u0638\u0631 \u0644\u0644\u0645\u062e\u0637\u0637 ( \u062f). \u062a\u0645 \u062a\u0623\u0643\u064a\u062f \u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0644\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629 \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629\u00a0 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 :\u0645\u0637\u064a\u0627\u0641\u064a\u0629 \u0627\u0644\u0627\u0634\u0639\u0629 \u062a\u062d\u062a \u0627\u0644\u062d\u0645\u0631\u0627\u0621, \u0648\u0627\u0644\u0623\u0637\u064a\u0627\u0641 \u0627\u0644\u0623\u0644\u0643\u062a\u0631\u0648\u0646\u064a\u0629 , \u0648\u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a (1<\/sup>H,13<\/sup>C) \u0648\u0645\u0637\u064a\u0627\u0641\u064a\u0629 \u0627\u0644\u0643\u062a\u0644\u0629 \u0648\u0627\u0644\u062a\u062d\u0644\u064a\u0644 \u0627\u0644\u062f\u0642\u064a\u0642 \u0644\u0644\u0639\u0646\u0627\u0635\u0631 \u0648 \u0641\u062d\u0635 \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a\u0629 , \u0627\u0644\u062a\u0648\u0635\u064a\u0644\u064a\u0629 \u0627\u0644\u0645\u0648\u0644\u0627\u0631\u064a\u0629 \u0648 \u0648\u062f\u0631\u062c\u0629 \u0627\u0644\u0627\u0646\u0635\u0647\u0627\u0631.<\/span><\/h4>\n

          <\/h4>\n

          \"\"\u0627\u0644\u0645\u062e\u0637\u0637 (\u062c) : \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0644\u062a\u062d\u0636\u064a\u0631 \u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0644\u0643\u0646\u062f \u0627\u0644\u0627\u0648\u0644 HL1<\/sup>.<\/span><\/h4>\n

          \"\"\u0627\u0644\u0645\u062e\u0637\u0637 (\u062f) : \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0644\u062a\u062d\u0636\u064a\u0631 \u0645\u0639\u0642\u062f\u0627\u062a \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u062b\u0627\u0646\u064a \u00a0H2<\/sub>L2<\/sup>.<\/span><\/h4>\n

          \u0648\u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a\u0629 \u0648\u0627\u0644\u0637\u064a\u0641\u064a\u0629 \u0627\u0642\u062a\u0631\u062d\u062a \u0627\u0644\u062a\u0631\u0627\u0643\u064a\u0628 \u0627\u0644\u0627\u062a\u064a\u0629:<\/span><\/h4>\n

          1- \u0643\u0627\u0646\u062a \u0645\u0639\u0642\u062f\u0627\u062a HL1<\/sup> \u0645\u0639 \u0627\u064a\u0648\u0646\u0627\u062a\u00a0 \u00a0Mn(\u04c0\u04c0)<\/sup>, Co(\u04c0\u04c0)<\/sup>, Ni(\u04c0\u04c0)<\/sup> and Cu(\u04c0\u04c0)<\/sup>\u00a0 \u0630\u0627\u062a \u062a\u0631\u0643\u064a\u0628 \u0627\u0648\u0643\u062a\u0627\u0647\u064a\u062f\u0631\u0627 \u0627\u0644\u0645\u0634\u0648\u0647.<\/span><\/h4>\n

          2- \u062a\u0631\u062a\u064a\u0628 \u0631\u0628\u0627\u0639\u064a\u0629 \u0627\u0644\u0633\u0637\u0648\u062d \u0645\u0639 \u0645\u0639\u0642\u062f\u0627\u062a Zn(II)<\/sup> Cd(II)<\/sup>.<\/span><\/h4>\n

          3- \u0627\u0634\u0643\u0627\u0644 \u062b\u0645\u0627\u0646\u064a\u0629 \u0627\u0644\u0633\u0637\u0648\u062d \u0645\u0634\u0648\u0647\u0647 \u062d\u0648\u0644 \u0627\u0644\u0627\u064a\u0648\u0646 \u0627\u0644\u0641\u0644\u0632\u064a \u0644\u0640 H2<\/sub>L2<\/sup> \u0645\u0639 \u0627\u064a\u0648\u0646\u0627\u062a Mn(\u04c0\u04c0)<\/sup>, Co(\u04c0\u04c0)<\/sup>, Ni(\u04c0\u04c0)<\/sup>, Cu(\u04c0\u04c0)<\/sup>, Zn(II) <\/sup>, Cd(II)<\/sup>.<\/span><\/h4>\n

          \u062a\u0645 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629 (\u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0627\u0644\u0641\u0644\u0632\u064a\u0629) \u0644\u0646\u0634\u0627\u0637\u0647\u0627 \u0627\u0644\u0645\u0627\u064a\u0643\u0631\u0648\u0628\u0627\u064a\u0648\u0644\u0648\u062c\u064a \u062a\u062c\u0627\u0647 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627\u00a0 \u0648\u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a. \u0648\u062a\u0634\u0645\u0644 \u0627\u0644\u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0629 \u0646\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u0633\u0644\u0627\u0644\u0627\u062a : \u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u064a\u062c\u0627\u0628\u064a\u0629\u00a0 \u0644\u0635\u0628\u063a\u0629 \u063a\u0631\u0627\u0645 : (Staphylococcus aureus<\/em>, Bacillus subtilis<\/em>)<\/span><\/h4>\n

          \u0648\u0633\u0627\u0644\u0628\u0629 \u0644\u0635\u0628\u063a\u0629 \u063a\u0631\u0627\u0645: (<\/em>Escherichia\u00a0coli <\/em>, Proteus spp<\/em>)<\/em><\/span><\/h4>\n

          \u062a\u0635\u064a\u0628 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0628\u0648\u0644\u064a \u0648\u0627\u0644\u062a\u0646\u0641\u0633\u064a \u0644\u0644\u0628\u0634\u0631 \u0648\u062a\u062d\u0633\u0628 \u0628\u0639\u0636\u0647\u0627 \u0643\u0646\u0648\u0639 \u0645\u0646 \u0627\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u0644\u0645\u0645\u064a\u062a\u0629 \u0648\u0627\u0644\u062a\u064a \u0645\u0645\u0643\u0646 \u0627\u0646 \u062a\u0646\u0634\u0637 \u0641\u064a \u063a\u0631\u0641\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629.<\/span><\/h4>\n

          \u0628\u0634\u0643\u0644 \u0639\u0627\u0645 \u060c \u062a\u0634\u064a\u0631 \u0627\u0644\u0627\u0633\u062a\u0646\u062a\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u0625\u0644\u0649 \u0623\u0646 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0627\u0633\u062a\u0646\u0628\u0627\u062a \u0623\u0638\u0647\u0631\u062a \u0645\u0639\u0642\u062f\u0627\u062a HL1<\/sup> \u00a0\u0646\u0634\u0627\u0637\u064b\u0627 \u0645\u0636\u0627\u062f\u064b\u0627 \u0644\u0644\u0645\u064a\u0643\u0631\u0648\u0628\u0627\u062a \u0636\u062f \u0645\u0639\u0638\u0645 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u060c \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f \u00a0\u0627\u0644\u062d\u0631. \u0623\u0638\u0647\u0631\u062a \u0645\u0639\u0642\u062f\u0627\u062a H2<\/sub>L2<\/sup> \u0646\u0634\u0627\u0637\u064b\u0627 \u0623\u0643\u0628\u0631 \u0636\u062f \u0628\u0639\u0636 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0633\u0644\u0627\u0644\u0627\u062a \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0629 \u060c \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u064a\u0643\u0627\u0646\u062f \u0627\u0644\u062d\u0631. \u0623\u0638\u0647\u0631 HL1<\/sup> \u0648 H2<\/sub>L2<\/sup> \u062a\u062b\u0628\u064a\u0637 \u062a\u062c\u0627\u0647 \u0646\u0648\u0639 \u0648\u0627\u062d\u062f \u0645\u0646 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 Proteus spp<\/em> \u0648 <\/em>Staphylococcus aureus<\/em> \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a.<\/em> \u064a\u0628\u062f\u0648 \u0627\u0646 \u0645\u0639\u0642\u062f\u0627\u062a HL1<\/sup>\u00a0 <\/sup>\u0644\u062f\u064a\u0647\u0627 \u0646\u0634\u0627\u0637 \u0645\u0636\u0627\u062f \u0644\u0644\u0628\u0643\u062a\u0631\u064a\u0627 \u0627\u0639\u0644\u0649 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u0639\u0642\u062f\u0627\u062a H2<\/sub>L2<\/sup>. \u0627\u0636\u0627\u0641\u0629 \u0627\u0644\u0649 \u0630\u0644\u0643 \u063a\u0637\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0641\u0637\u0631\u064a\u0627\u062a \u0644\u0646\u0648\u0639\u064a\u0646 \u0645\u0646\u0647\u0627: \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0627\u0648\u0644 \u0647\u0648 Candida albicans<\/em> \u0648\u064a\u0635\u064a\u0628 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a \u0648\u0627\u0644\u0641\u0645 \u0641\u064a 40-60% \u0645\u0646 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0627\u0635\u062d\u0627\u0621. \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u0647\u0648 Trichophyton rubrum<\/em> \u0648\u064a\u0633\u0628\u0628 \u0627\u0644\u062a\u0647\u0627\u0628 \u062c\u0631\u064a\u0628\u0627\u062a \u0627\u0644\u0634\u0639\u0631 \u0641\u064a \u0627\u0644\u0630\u0642\u0646 \u0648 \u0641\u0631\u0648\u0629 \u0627\u0644\u0631\u0623\u0633 \u0648\u0627\u0644\u0645\u0633\u0624\u0648\u0644 \u0639\u0646 \u0627\u0635\u0627\u0628\u0629 \u0627\u0644\u0642\u062f\u0645 \u0627\u0644\u0631\u064a\u0627\u0636\u064a. \u0627\u0634\u0627\u0631\u062a \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0649 \u0645\u0642\u0627\u0648\u0645\u0629 \u0641\u0637\u0631\u064a\u0627\u062a<\/em> Trichophyton rubrum<\/em> \u0641\u064a \u0643\u0644\u0627 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u064a\u0646 . \u064a\u0638\u0647\u0631<\/em> H2<\/sub>L2<\/sup> \u0646\u0634\u0627\u0637\u0627 \u0645\u0636\u0627\u062f <\/em>\u0636\u062f \u0646\u0648\u0639 Candida albicans<\/em>\u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0640 \u00a0<\/em>HL1<\/sup>. \u0623\u0634\u0627\u0631\u062a \u0645\u0639\u0642\u062f\u0627\u062a \u00a0HL1<\/sup> \u0627\u0644\u0641\u0644\u0632\u064a\u0629 \u00a0\u0625\u0644\u0649 \u0646\u0634\u0627\u0637 \u0623\u0639\u0644\u0649 \u062a\u062c\u0627\u0647 \u0627\u0644\u0641\u0637\u0631\u064a\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0645 \u0641\u062d\u0635\u0647\u0627 \u060c \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u062d\u0631\u0629 \u0627\u0644\u0645\u0634\u062a\u0642\u0629 \u0645\u0646\u0647\u0627. \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0645 \u062c\u0645\u0639\u0647\u0627 \u0623\u0646 H2<\/sub>L2<\/sup> \u064a\u0639\u062a\u0628\u0631 \u0623\u0643\u062b\u0631 \u0646\u0634\u0627\u0637\u064b\u0627 \u0636\u062f Candida albicans<\/em> \u060c \u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0645\u0639\u0642\u062f\u0627\u062a\u0647 \u0627\u0644\u0641\u0644\u0632\u064a\u0629.\u00a0 <\/em>\u00a0\u00a0<\/em>\u00a0<\/span><\/h4>\n

          <\/h4>\n

          <\/h4>\n

          \u0648\u062e\u0644\u0635 \u0627\u0644\u0637\u0627\u0644\u0628 \u0627\u0644\u0649 \u0627\u0644\u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u0627\u062a\u064a\u0629 :<\/span><\/h4>\n
            \n
          1. \n

            \u062a\u062d\u0636\u064a\u0631 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0645\u0627\u0646\u062e \u0648\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u062b\u0627\u064a\u0648\u0633\u064a\u0645\u064a\u0643\u0627\u0631\u0628\u0627\u0632\u0648\u0646 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0627\u0648\u0644\u064a\u0629 \u0648\u0628\u062f\u0627\u0626\u0644 \u0645\u062e\u062a\u0644\u0641\u0629<\/span><\/h4>\n<\/li>\n
          2. \n

            \u062a\u062d\u0636\u064a\u0631 \u0645\u0639\u0642\u062f\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0627\u0639\u0644\u0627\u0647 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u064a\u0648\u0646\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u0645\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0644\u064a\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u062b\u0627\u0644\u062b\u0629<\/span><\/h4>\n<\/li>\n
          3. \n

            \u0627\u0644\u0639\u0645\u0644 \u0639\u0644\u0649 \u0627\u0639\u0627\u062f\u0629 \u0628\u0644\u0648\u0631\u0629 \u0648\u062a\u0643\u0648\u064a\u0646 \u0628\u0644\u0648\u0631\u0629 \u0645\u0646\u0627\u0633\u0628\u0629 \u0644\u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0648\u0645\u0639\u0642\u062f\u0627\u062a\u0647\u0627 \u0645\u0646 \u0627\u062c\u0644 \u062a\u062d\u062f\u064a\u062f \u0627\u0634\u0643\u0627\u0644\u0647\u0627 \u0645\u0646 \u062e\u0644\u0627\u0644 X-ray single crystal<\/span><\/h4>\n<\/li>\n
          4. \n

            \u0641\u062d\u0635 \u0627\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629 \u0636\u062f \u0643\u0627\u0626\u0646\u0627\u062a \u062f\u0642\u064a\u0642\u0629 \u0627\u062e\u0631\u0649<\/span><\/h4>\n<\/li>\n
          5. \n

            \u0627\u0644\u062a\u062d\u0642\u064a\u0642 \u0641\u064a \u0627\u0646\u0634\u0637\u0627\u0631 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0648\u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0633\u0631\u0637\u0627\u0646 \u0644\u0644\u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u0636\u0631\u0629<\/span><\/h4>\n<\/li>\n<\/ol>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            New metal complexes derived from Mannich ligands ; synthesis, spectral\u00a0 investigation and biological evaluation\u00a0\u00a0 <\/em><\/span><\/h4>\n

            Ammar\u00a0 Hassan\u00a0 Abdulhadi\u00a0 Mahdi\u00a0 Al-Qazzaz<\/span><\/h4>\n

            Prof. Dr. Mohamad J. Al-Jeboori \\ Department of Chemistry<\/span><\/h4>\n

            <\/h4>\n

            <\/h4>\n

            <\/h4>\n

            Aim of the work<\/span><\/h4>\n
              \n
            • \n

              Synthesis of new bidentate Mannich-base ligand namely; (2R)-2-((R)-(4(dimethylamino)phenyl)(phenylamino)methyl)-4methylcyclohexan-1-one (HL1<\/sup>) from mixing of a three organic component (p<\/em>-methylecyclohexanone, phenylamine, p<\/em>-dimethylaminobenzaldehyde).<\/span><\/h4>\n<\/li>\n
            • \n

              Synthesis of new tridentate thiosemicarbazone Schiff-base ligand namely; (E)-2-((2S)-2-((S)-(4(dimethylamino)phenyl) (phenylamino)methyl))-4-methylcyclohexylidene)hydrazine-1-carbothioamide (H2<\/sub>L2<\/sup>) by mixing HL1<\/sup> with thiosemicarbazide.<\/span><\/h4>\n<\/li>\n
            • \n

              Synthesis of a range of metal complexes from the reaction of both ligands with Mn(II)<\/sup>, Co(II)<\/sup>, Ni(II)<\/sup>,\u00a0 Cu(II)<\/sup>,\u00a0 Zn(II)<\/sup> and\u00a0 Cd(II)<\/sup>, ions.<\/span><\/h4>\n<\/li>\n
            • \n

              Studying the possible structures and the stereochemistry of ligands and complexes.<\/span><\/h4>\n<\/li>\n
            • \n

              Exploring the microbiological activity of ligands and their complexes against G+<\/sup> and G–<\/sup> strains of bacteria and two types of fungi.<\/span><\/h4>\n<\/li>\n<\/ul>\n

              Abstract :<\/span><\/h4>\n

              This study includes the formation, structural characterisation and biological activity of\u00a0 two ligands and their metal complexes. The preparation of ligand (2R)-2-((R)-(4(dimethylamino)phenyl) (phenylamino)methyl)-4-methyl cyclohexan-1-one (HL1<\/sup>) was accomplished through a one-pot reaction derived from Mannich approach in which CaCl2<\/sub> was used as a catalyst. The reaction was achieved in EtOH by mixing three components; p<\/em>-dimethylaminobenzaldehyde, aniline and p<\/em>-methylcyclohexanone with a 1:1:1 mole ratio. The resulting mixture was stirred for 12 h at\u00a0 room temperature. The title \u00a0product was obtained as a solid material that filtered off, washed with distilled water, recrystallized from EtOH \u00a0and then dried under vacuum, see Scheme(I). The synthesis of second ligand H2<\/sub>L2<\/sup> was performed by the condensation reaction of the ketone group of HL1<\/sup> with the amine group of the thiosemicarbazide moiety. In the formation of H2<\/sub>L2<\/sup> ((E)-2-((2S)-2-((S)-(4(dimethylamino)phenyl)(phenylamino)methyl)-4-methyl cyclohexylidene) hydrazine-1carbothioamide) (H2<\/sub>L2<\/sup>). The fabrication of H2<\/sub>L2<\/sup> was derived from the addition of a 1 equivalent of an ethanolic solution of thiosemicarbazide to an equivalent mole ratio of HL1<\/sup> at reflux for 5 h that resulted in the isolation of H2<\/sub>L2<\/sup> in a moderate yield. The solid product was filtered off then washed with ethanol and ether, Scheme (I).<\/span><\/h4>\n

              <\/h4>\n

              \u00a0\u00a0\u00a0\u00a0 Scheme (I): General synthetic steps of HL1<\/sup> and H2<\/sub>L2<\/sup>.<\/span><\/h4>\n

              \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/h4>\n

              The prepared ligands were used to synthesize a range of complexes with Mn(II)<\/sup>, Co(II)<\/sup>, Ni(II)<\/sup>, Cu(II)<\/sup>, Zn(II)<\/sup> and Cd(II)<\/sup> ions in a 1:2 (M:L) mole ratio using ethanol or DMF as a solvent. The resulting mixture was stirred for 24 h at room temperature. The solution was allowed to evaporate\u00a0 slowly at RT and a coloured solid powder was formed, which\u00a0 filtered off, washed with chloroform\u00a0 and diethylether. The HL1<\/sup> gave monomeric complexes with the title metal ion of the general formula [Mn(HL1<\/sup>)2<\/sub>(Cl)2<\/sub>], [M(HL1<\/sup>)2<\/sub>(Cl)2<\/sub>].(H2<\/sub>O) (where M= Co(II)<\/sup>, Ni(II)<\/sup>, Cu(II)<\/sup> , [Zn(HL1<\/sup>)]Cl2<\/sub>.(H2<\/sub>O) and [Cd(HL1<\/sup>)]Cl2<\/sub>, see Scheme (II). The H2<\/sub>L2<\/sup> gave polymeric complexes upon reaction with the title metal ion of the general formula {[M(HL2<\/sup>)2<\/sub>]Cl2<\/sub>}n<\/sub>, see Scheme (III). The chemical structure of the entity ligands and their metal complexes were confirmed using; FT-IR, electronic spectra, 1<\/sup>H- and 13<\/sup>C-NMR spectra, electrospray mass spectroscopy, elemental analysis, magnetic susceptibility, molar conductivity and melting point.<\/span><\/h4>\n

              <\/h4>\n

              Scheme (II): General synthetic route of HL1<\/sup> complexes.<\/span><\/h4>\n

              Scheme (III): General synthetic route of H2<\/sub>L2<\/sup> complexes.<\/span><\/h4>\n

              <\/h4>\n

              Based on the analytical and spectroscopic data, the following structures are suggested:<\/span><\/h4>\n
                \n
              1. \n

                HL1<\/sup> complexes with Mn(\u04c0\u04c0)<\/sup>, Co(\u04c0\u04c0)<\/sup>, Ni(\u04c0\u04c0)<\/sup> and Cu(\u04c0\u04c0)<\/sup> ions indicated the formation of six coordinate complexes with distorted octahedral geometry around metal centre.<\/span><\/h4>\n<\/li>\n
              2. \n

                A tetrahedral arrangement was suggested with Zn(II)<\/sup> and Cd(II)<\/sup><\/span><\/h4>\n<\/li>\n
              3. \n

                H2<\/sub>L2<\/sup> complexes with Mn(\u04c0\u04c0)<\/sup>, Co(\u04c0\u04c0)<\/sup>, Ni(\u04c0\u04c0)<\/sup>, Cu(\u04c0\u04c0)<\/sup>, Zn(II) <\/sup>and Cd(II) <\/sup>ions revealed the isolation of distorted octahedral geometry about metal core.<\/span><\/h4>\n<\/li>\n<\/ol>\n

                <\/h4>\n

                \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 The prepared compounds (ligands and their metal complexes) have evaluated for their microbiological activity toward a range of bacteria and fungi microorganism. The bacterial species include two type of strains : G-positive (Staphylococcus aureus<\/em>, Bacillus subtilis<\/em>) and G-negative (<\/em>Escherichia\u00a0coli <\/em>, Proteus spp<\/em>)<\/em>. The examined bacteria in this work have the ability to infect the urinary and respiratory tract of humans and account as the nasty and deadly type of bacteria that found in the surgery operation room. Generally, anti-bacterial activity data show that the complexes of HL1<\/sup> exhibited antimicrobial activity against most bacterial species, compared with the free ligand. The complexes of H2<\/sub>L2<\/sup> exhibited enhanced activity against some types of the bacterial strains, compared with the free ligand. HL1<\/sup> and H2<\/sub>L2<\/sup> showed inhibition activity towards one kind of bacteria; Proteus spp <\/em>and Staphylococcus aureus<\/em>, respectively. The HL1<\/sup> complexes appeared to have the highest anti-bacterial activity, compared with the H2<\/sub>L2<\/sup> complexes. More, the activity against fungal species covered two types of fungi. The first species Candida albicans<\/em> is detected in the gastrointestinal tract and mouth in 40\u201360% of healthy adults. The second species Trichophyton rubrum<\/em>\u00a0 has the ability to infect the feet scalp and it is responsible for athlete’s foot infection. The obtained data indicated the resistance of Trichophyton rubrum<\/em> against both ligands. More, H2<\/sub>L2<\/sup> shows activity against Candida albicans<\/em> compared with HL1<\/sup>. The HL1<\/sup> metal complexes indicated higher activity towards the examined fungi, compared with the free ligand. \u00a0\u00a0Based on data, H2<\/sub>L2<\/sup> indicated to be more active against Candida albicans<\/em>, compared with its complexes.<\/span><\/h4>\n

                <\/h4>\n

                <\/h4>\n

                <\/h4>\n

                <\/h4>\n

                Prospective studies<\/span><\/h4>\n
                  \n
                1. \n

                  Formation of new Mannich-base and thiosemicarbazone ligands with a variety of starting materials and different substituents.<\/span><\/h4>\n<\/li>\n
                2. \n

                  Formation of new metal complexes with the above ligands using transition metal ions including that from the second and\/or third series of transition ions.<\/span><\/h4>\n<\/li>\n
                3. \n

                  Working on the recrystallization of the ligands and their metal complexes in order to isolated crystals that suitable for X-ray single crystal structure.<\/span><\/h4>\n<\/li>\n
                4. \n

                  Screening the prepared compounds against other microorganism.<\/span><\/h4>\n<\/li>\n
                5. \n

                  Investigating the DNA cleavage and anti-cancer activity of the prepared compounds.<\/span><\/h4>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

                  \u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 ( \u0645\u0639\u0642\u062f\u0627\u062a \u0641\u0644\u0632\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0644\u064a\u0643\u0627\u0646\u062f\u0627\u062a….<\/i>\u0627\u0644\u0645\u0632\u064a\u062f<\/span><\/a><\/p>\n","protected":false},"author":25,"featured_media":32478,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[7,16],"tags":[23,47],"class_list":["post-32466","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","category-16","tag-ihcoedu","tag-chem"],"modified_by":"ihcoedu","_links":{"self":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/32466","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=32466"}],"version-history":[{"count":0,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/32466\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/32478"}],"wp:attachment":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=32466"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=32466"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=32466"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}