{"id":38869,"date":"2021-09-19T12:21:33","date_gmt":"2021-09-19T09:21:33","guid":{"rendered":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=38869"},"modified":"2021-09-22T11:51:32","modified_gmt":"2021-09-22T08:51:32","slug":"%d9%82%d8%b3%d9%85-%d8%a7%d9%84%d9%83%d9%8a%d9%85%d9%8a%d8%a7%d8%a1-%d9%8a%d9%86%d8%a7%d9%82%d8%b4-%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1%d8%aa%d8%af%d8%b1%d8%b3","status":"publish","type":"post","link":"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=38869","title":{"rendered":"\u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u064a\u0646\u0627\u0642\u0634 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631\u062a\u062f\u0631\u0633 \u062f\u0648\u0631 \u0627\u0644\u0645\u064a\u0644\u0627\u062a\u0648\u0646\u064a\u0646 \u0648 \u0646 &#8211; \u0623\u0633\u064a\u062a\u0627\u0644 \u0643\u0627\u0644\u0627\u0643\u062a\u0648\u0632\u0627\u0645\u064a\u0646\u064a\u0644 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srcset=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2021\/09\/\u0639\u0628\u0627\u0633-\u0639\u0628\u062f-\u0631\u062f\u0627\u0645-4.jpg 1024w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2021\/09\/\u0639\u0628\u0627\u0633-\u0639\u0628\u062f-\u0631\u062f\u0627\u0645-4-300x200.jpg 300w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2021\/09\/\u0639\u0628\u0627\u0633-\u0639\u0628\u062f-\u0631\u062f\u0627\u0645-4-768x512.jpg 768w, https:\/\/ihcoedu.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/27\/2021\/09\/\u0639\u0628\u0627\u0633-\u0639\u0628\u062f-\u0631\u062f\u0627\u0645-4-600x400.jpg 600w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/h4>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000080;\">\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 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\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0639\u0644\u0649 \u0627\u0644\u063a\u0630\u0627\u0621 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0627\u0644\u063a\u0646\u064a \u0628\u0627\u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646\u0627\u062a \u0648\u0645\u0645\u0627\u0631\u0633\u0629 \u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0648\u0627\u0644\u062a\u0639\u0631\u0636 \u0644\u0623\u0634\u0639\u0629 \u0627\u0644\u0634\u0645\u0633.<\/span><\/h4>\n<\/li>\n<\/ul>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000080;\">2- \u062a\u062d\u062f\u064a\u062f \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0644\u0648\u062a\u064a\u0646\u064a \u0648\u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0645\u0646\u0628\u0647 \u0644\u0644\u062c\u0631\u064a\u0628 \u0641\u064a \u0645\u0635\u0644 \u0627\u0644\u0627\u0646\u0627\u062b \u0627\u0644\u0639\u0631\u0627\u0642\u064a\u0627\u062a \u0627\u0644\u0645\u0635\u0627\u0628\u0627\u062a \u0628\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0639\u0635\u0628 \u0627\u0644\u062e\u0627\u0645\u0633.<\/span><\/h4>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000080;\">3- \u064a\u062c\u0628 \u0625\u0628\u0631\u0627\u0632 \u0627\u0644\u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u0643\u064a\u0645\u0648\u062d\u064a\u0648\u064a\u0629 \/ \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0644\u0645\u064a\u0644\u0627\u062a\u0648\u0646\u064a\u0646 \u060c \u0648\u0627\u0644\u0643\u0648\u0644\u0627\u062c\u064a\u0646 \u060c \u0648 \u0646- \u0623\u0633\u064a\u062a\u064a\u0644 \u062c\u0627\u0644\u0627\u0643\u062a\u0648\u0632\u0627\u0645\u064a\u0646\u064a\u0644 \u062a\u0631\u0627\u0646\u0633\u0641\u064a\u0631\u064a\u0632 12 \u060c \u0648\u0627\u0644\u0632\u0646\u0643 \u0641\u064a \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0639\u0635\u0628 \u0627\u0644\u062e\u0627\u0645\u0633 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u062a\u0646\u0643\u0633\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0627\u0644\u0623\u062e\u0631\u0649 \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0630\u0627\u062a\u064a\u0629.<\/span><\/h4>\n<hr \/>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">The role of melatonin, N- acetyl galactosaminyl transferase 12 and\u00a0 other biochemical parameters in sera of Iraqi patients with Trigeminal Neuralgia before and after treatment with tegretol<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">By Abbas Abed Radam Lilo<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">Supervised by Assistant ProfessorDr. Rasha Zuhair Jasim<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">The aim of the present study<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">To indicate and supports\u00a0 the biochemical findings related to the relationship between (Vitamin B12, Vitamin D and IgG) and TN before and after treatment\u00a0 with tegretol (carbamazepine) for both genders<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">To find a novel\u00a0 biochemical relationship between (melatonin, collagen I,GALNT12 and Zn )and TN and highlight the biochemical role of tegretol (carbamazepine) on the above parameters for both genders.<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">Summary<\/span><\/h3>\n<h3 style=\"text-align: left;\"><span style=\"color: #993366;\">Trigeminal Neuralgia (TN) is one of the most commonly painful cranial neuralgia characterized by paroxysmal attacks as short lasting facial pain along the trigeminal nerve branches. The aim of the present study is to innovate a biochemical relationship between (melatonin , collagen I , GALNT12 and Zn) and TN, investigate and indicate the biochemical relationship between (Vitamin B12, vitamin D3 and IgG) and TN and also to examine the biochemical action of tegretol (carbamazepine) as a treatment on the above biochemical parameters. Blood samples were collected from fifty four (54) trigeminal neuralgia patients diagnosed by magnetic radiation image (MRI). Patients were classified into four groups : G3 (40- 70) years composed of (12) diagnosed male (without treatment) , G4 (48- 75) years composed of (12) diagnosed female ( without treatment), G5 (34- 76) years composed of (15) male under treatment with tegretol (200 mg \/daily) and G6 (49-65) years composed of (15) female under treatment with tegretol (200 mg\/ daily). Patients were compared with healthy subjects (have approximately the same range of age) as control groups : G1 composed of (15) males (43-70) years and G2 composed of (15) females (50-55) years. The present study submits a good indication to the field of research regarding the lower levels of vitamin B12 and vitamin D3 in TN patients before and after treatment with tegretol (carbamazepine). The present study is the first reporting that melatonin is a novel biochemical marker in Iraqi patients with TN (with significant and highly significant decrease in males and females respectively compared with healthy subjects). Also it is the first reporting that collagen, GALNT12 and Zn are novelbiochemical markers in Iraqi patients with TN (with highly significant decrease in both genders compared with healthy subjects). The present study is the first highlighting and dealing with the biochemical action of tegretol (carbamazepine) on melatonin, collagen I, GALNT12 and Zn by submitting unique and novel mechanisms.\u00a0 Moreover, the present study suggests that IgG level is a good biochemical marker in Iraqi male subjects and investigates its relationship with tegretol (carbamazepine).<\/span><\/h3>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0646\u0627\u0642\u0634 \u0642\u0633\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0631\u0628\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0635\u0631\u0641\u0629 (\u0627\u0628\u0646 \u0627\u0644\u0647\u064a\u062b\u0645) \u0631\u0633\u0627\u0644\u0629 \u0627\u0644\u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0627\u0644\u0645\u0648\u0633\u0648\u0645\u0629 (\u062f\u0648\u0631 \u0627\u0644\u0645\u064a\u0644\u0627\u062a\u0648\u0646\u064a\u0646&#8230;.<a class=\"cz_readmore\" href=\"https:\/\/ihcoedu.uobaghdad.edu.iq\/?p=38869\"><i class=\"fa fa-angle-left\" aria-hidden=\"true\"><\/i><span>\u0627\u0644\u0645\u0632\u064a\u062f<\/span><\/a><\/p>\n","protected":false},"author":25,"featured_media":38871,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","footnotes":""},"categories":[7,59,16],"tags":[23,47],"class_list":["post-38869","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-7","category-59","category-16","tag-ihcoedu","tag-chem"],"modified_by":"ihcoedu","_links":{"self":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/38869","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38869"}],"version-history":[{"count":0,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/38869\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/38871"}],"wp:attachment":[{"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38869"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=38869"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ihcoedu.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=38869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}